L6 + IGF Cell Lysate: sc-24727

L6 + IGF cell lysate is derived from L6 myoblasts treated with insulin-like growth factor (IGF), facilitating detailed studies on muscle cell differentiation and growth. This specific lysate is instrumental in exploring how IGF signaling influences muscle cell biology, particularly its role in stimulating protein synthesis and inhibiting protein degradation, key processes in muscle growth and repair. Researchers utilize this lysate to dissect the signaling pathways activated by IGF, notably the PI3K/Akt pathway, which is crucial for mediating the effects of IGF on cell proliferation and survival. Additionally, this treatment promotes the differentiation of myoblasts into myotubes, an essential process for muscle formation and regeneration. The L6 + IGF lysate helps in investigating the modulation of myogenic regulatory factors such as MyoD and myogenin, which are vital for the differentiation process. Studies using this lysate contribute to understanding the cellular and molecular mechanisms of muscle metabolism and growth, providing insights into muscle physiology and the basic mechanisms of hypertrophy.