Date published: 2026-6-6

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L-Tyrosine amide (CAS 4985-46-0)

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CAS Number:
4985-46-0
Molecular Weight:
180.2
Molecular Formula:
C9H12N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Tyrosine amide is a modified amino acid that serves as a compound in biochemistry and organic synthesis. It is used as a substrate in enzymatic studies to understand the specificity and mechanism of proteases, which cleave amide bonds. In peptide synthesis, L-Tyrosine amide is to analyze the impact of the amide group on peptide stability, solubility, and conformation. L-Tyrosine amide in studies of post-translational modifications, particularly amidation, which is critical for the function and activity of many proteins. L-Tyrosine amide is of interest in the design of biomimetic materials, where it can be incorporated into polymers to introduce sites that mimic L-Tyrosine amide functionality of proteins. The compound also plays a role in the development of new methods for the solid-phase synthesis of peptides, where it can be used to investigate the efficiency of peptide bond formation under various conditions.


L-Tyrosine amide (CAS 4985-46-0) References

  1. Unfolding and refolding of juvenile hormone binding protein.  |  Dobryszycki, P., et al. 2004. Biophys J. 86: 1138-48. PMID: 14747348
  2. Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptors.  |  Huynh, PN., et al. 2020. Biochem Pharmacol. 181: 114124. PMID: 32593612
  3. Structure-Based Evolution of G Protein-Biased μ-Opioid Receptor Agonists.  |  Wang, H., et al. 2022. Angew Chem Int Ed Engl. 61: e202200269. PMID: 35385593
  4. Thiol-ene photoimmobilization of chymotrypsin on polysiloxane gels for enzymatic peptide synthesis.  |  Wang, M., et al. 2018. RSC Adv. 8: 11843-11849. PMID: 35539381
  5. Partial purification and properties of an enzyme from rat liver that catalyses the sulphation of L-tyrosyl derivatives.  |  Mattock, P. and Jones, JG. 1970. Biochem J. 116: 797-803. PMID: 5441369

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Tyrosine amide, 1 g

sc-286115
1 g
$49.00

L-Tyrosine amide, 5 g

sc-286115A
5 g
$168.00