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L-type Ca<sup>++</sup> CP &beta;2 Antibody (F-29) - Western Blotting - Image 33540
L-type Ca++ CP β2 (F-29): sc-81890. Western blot analysis of L-type Ca++ CP β2 expression in Jurkat whole cell lysate.
L-type Ca++ CP β2 Antibody (F-29) - Western Blotting - Image 33540
L-type Ca++ CP β2 (F-29): sc-81890. Western blot analysis of L-type Ca++ CP β2 expression in Jurkat whole cell lysate.
L-type Ca++ CP β2 (F-29): sc-81890. Western blot analysis of L-type Ca++ CP β2 expression in Jurkat whole cell lysate.

L-type Ca++ CP β2 Antibody (F-29): sc-81890

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Datasheets
  • L-type Ca++ CP β2 Antibody (F-29) is a mouse monoclonal IgG1 κ L-type Ca++ CP β2 antibody, cited in 3 publications, provided at 100 µg/ml
  • raised against recombinant L-type Ca++ CP β2 of human origin
  • recommended for detection of L-type Ca++ CP β2 of mouse, rat and human origin by WB, IP and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for L-type Ca++ CP β2 Antibody (F-29). This work is in progress.
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Additional Calcium Channel Protein Antibodies including L-type Ca++ CP α 1F, L-type Ca++ CP α 1S, L-type Ca++ CP β 1A, L-type Ca++ CP β 2, L-type Ca++ CP β 3, L-type Ca++ CP β 4, L-type Ca++CP γ 2, L-type Ca++CP γ 3, L-type Ca++CP γ 8, N-type Ca++ CP α 1B, P/Q-type Ca++ CP α 1A, T-type Ca++ CP α 1H and T-type Ca++ CP α 1I

L-type Ca++ CP β2 Antibody (F-29) is a mouse monoclonal IgG1 kappa light chain antibody that detects L-type Ca++ CP beta 2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-L-type Ca++ CP beta 2 antibody (F-29) is available as a non-conjugated format. L-type Ca++ CP beta 2 protein plays a crucial role in calcium channel function, essential for various physiological processes, including muscle contraction, hormone secretion, and neurotransmitter release. Calcium channels are composed of multiple subunits, including an alpha-1 subunit forming the channel pore, an intracellular beta subunit modulating channel activity, and auxiliary subunits influencing channel properties and localization. Proper functioning of L-type calcium channels maintains cellular excitability and signaling by facilitating calcium ion influx in response to membrane depolarization. L-type calcium channels interact with specific proteins, such as G protein-coupled receptors, enhancing signaling pathway specificity and contributing to macromolecular signaling complex formation. The gamma-2 subunit, also known as stargazin, regulates synaptic targeting of AMPA receptors in the brain, influencing synaptic transmission and plasticity. This protein interaction network highlights L-type Ca++ CP beta 2′s significance in normal cellular function and potential pathophysiological conditions.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

L-type Ca++ CP β2 Antibody (F-29) References:

  1. Structure and regulation of voltage-gated Ca2+ channels.  |  Catterall, WA. 2000. Annu Rev Cell Dev Biol. 16: 521-55. PMID: 11031246
  2. Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms.  |  Chen, L., et al. Nature. 408: 936-43. PMID: 11140673
  3. A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2.  |  Davare, MA., et al. 2001. Science. 293: 98-101. PMID: 11441182
  4. Molecular biology of calcium channels.  |  Perez-Reyes, E. and Schneider, T. 1995. Kidney Int. 48: 1111-24. PMID: 8569073
  5. The molecular basis of voltage-gated Ca2+ channel diversity: is it time for T?  |  Randall, AD. 1998. J Membr Biol. 161: 207-13. PMID: 9493126
  6. The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit.  |  Letts, VA., et al. 1998. Nat Genet. 19: 340-7. PMID: 9697694

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-type Ca++ CP β2 Antibody (F-29)

sc-81890
100 µg/ml
$339.00

What is the recommended storage condition for L-type Ca++ CP &beta;2 (F-29): sc-81890?

Asked by: DefinitelyNotMatt
Thank you for your question. We recommend storing the antibody at 4&deg; C.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by from Good for Western BlotThis antibody has been used for western blotting in published research. -SCBT QC
Date published: 2023-09-14
Rated 4 out of 5 by from Good signal in WB in HEK whole cell lysateGood signal strength in WB, but not selective through the beta isoforms. Also the beta 3 subunit will be detected in transfected HEK cells.
Date published: 2021-08-23
Rated 4 out of 5 by from Good specificity in WB in Jurkat whole cell lysateGood specificity in WB in Jurkat whole cell lysate. -SCBT QC
Date published: 2015-02-28
Rated 4 out of 5 by from Published WB data with mouse vascular smoothPublished WB data with mouse vascular smooth muscle cells - SCBT Publication Review
Date published: 2013-06-29
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L-type Ca ++ CP β2 Antibody (F-29) is rated 4.3 out of 5 by 4.
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