L-type Ca⁺⁺ CP β1 Antibody (Y-2D68): sc-134377

L-type Ca++ CP β1 Antibody (Y-2D68) is a mouse monoclonal IgG2a kappa light chain antibody that detects L-type Ca++ CP beta 1 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-L-type Ca++ CP beta 1 antibody (Y-2D68) is available as non-conjugated format. L-type Ca++ CP beta 1 plays a crucial role in voltage-dependent calcium channels, which are essential for mediating calcium entry into excitable cells in response to membrane depolarization. This process is vital for various calcium-dependent physiological functions, including muscle contraction, hormone and neurotransmitter release, and gene expression. L-type Ca++ CP beta 1 is part of a complex structure that includes an α-1 subunit, an intracellular β-subunit, a disulfide-linked α-2/δ subunit, and a transmembrane γ-subunit, which together contribute to the diverse biophysical and pharmacological properties of calcium currents. Notably, L-type calcium channels are involved in initiating muscle contraction and endocrine secretion, and can be modulated through second-messenger pathways, highlighting their importance in cellular signaling. L-type Ca++ CP beta 1 may interact with G protein-coupled receptors, forming macromolecular signaling complexes that enhance the specificity of target regulation, making this protein a significant player in cellular communication and function.

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L-type Ca⁺⁺ CP β1 Antibody (Y-2D68) References:

1. Structure and regulation of voltage-gated Ca2+ channels.  |  Catterall, WA. 2000. Annu Rev Cell Dev Biol. 16: 521-55. PMID: 11031246
2. A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2.  |  Davare, MA., et al. 2001. Science. 293: 98-101. PMID: 11441182
3. Molecular biology of calcium channels.  |  Perez-Reyes, E. and Schneider, T. 1995. Kidney Int. 48: 1111-24. PMID: 8569073
4. The molecular basis of voltage-gated Ca2+ channel diversity: is it time for T?  |  Randall, AD. 1998. J Membr Biol. 161: 207-13. PMID: 9493126

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-L-type Ca⁺⁺ CP β1 Antibody (Y-2D68) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-L-type Ca⁺⁺ CP β1 Antibody (Y-2D68) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

L-type Ca⁺⁺ CP β1 Antibody (Y-2D68) Specifications

Alternate Product Name: L-type Ca++ CP β1

Product Clone Name: Y-2D68

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 500-599

Epitope Target: L-type Ca++ CP β1

Epitope Species: human

Product Reactivity/Detection: L-type Ca++ CP β1

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for L-type Ca⁺⁺ CP β1 Antibody (Y-2D68): N/A