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L-type Ca++ CP α1F Antibody (1H6): sc-517005

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Datasheets
  • L-type Ca++ CP α1F Antibody (1H6) is a mouse monoclonal IgG3 κ L-type Ca++ CP α1F antibody, cited in 1 publications, provided at 100 µg/ml
  • raised against amino acids 1878-1977 representing partial length Ca++ CP α1F 1F of human origin
  • recommended for detection of L-type Ca++ CP α1F of human origin by WB, IP and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for L-type Ca++ CP α1F Antibody (1H6). This work is in progress.

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L-type Ca++ CP α1F Antibody (1H6) is a mouse monoclonal IgG3 kappa light chain antibody that detects the L-type Ca++ CP alpha 1F protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-L-type Ca++ CP alpha 1F antibody (1H6) is available as the non-conjugated format. L-type Ca++ CP alpha 1F protein plays a crucial role in regulating calcium ion entry into excitable cells, which is essential for various physiological processes such as muscle contraction, hormone secretion, and neurotransmitter release. L-type Ca++ CP alpha 1F protein is primarily located in the plasma membrane of excitable cells, where L-type Ca++ CP alpha 1F protein forms part of the voltage-dependent calcium channel complex. Proper functioning of these channels is vital, as voltage-dependent calcium channels facilitate calcium ion influx in response to membrane depolarization, triggering downstream signaling pathways that lead to critical cellular responses. L-type calcium channels interact with various signaling molecules, including G protein-coupled receptors, which can modulate channel activity and enhance calcium signaling specificity in different cellular contexts. L-type Ca++ CP α1F monoclonal antibody (1H6) enables researchers to gain valuable insights into calcium signaling mechanisms and their implications in health and disease.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

L-type Ca++ CP α1F Antibody (1H6) References:

  1. Structure and regulation of voltage-gated Ca2+ channels.  |  Catterall, WA. 2000. Annu Rev Cell Dev Biol. 16: 521-55. PMID: 11031246
  2. A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2.  |  Davare, MA., et al. 2001. Science. 293: 98-101. PMID: 11441182
  3. Molecular biology of calcium channels.  |  Perez-Reyes, E. and Schneider, T. 1995. Kidney Int. 48: 1111-24. PMID: 8569073
  4. The molecular basis of voltage-gated Ca2+ channel diversity: is it time for T?  |  Randall, AD. 1998. J Membr Biol. 161: 207-13. PMID: 9493126

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-type Ca++ CP α1F Antibody (1H6)

sc-517005
100 µg/ml
$316.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with L-type Ca++ CP α1F (1H6): sc-517005 antibody?

Asked by: jenniferc
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by from Good for Western blotAntibody detects human recombinant L-type Ca++ CP α1F by Western blot. -SCBT QC
Date published: 2023-09-14
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L-type Ca ++ CP α1F Antibody (1H6) is rated 5.0 out of 5 by 1.
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