Date published: 2025-9-29

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L-Tryptophan (CAS 73-22-3)

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Alternate Names:
Trofan; Tryptacin; Ardeytropin
Application:
L-Tryptophan is An essential amino acid
CAS Number:
73-22-3
Molecular Weight:
204.25
Molecular Formula:
C11H12N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Tryptophan, also known as Tryptophan, is involved in numerous biological processes. Beyond its role in constructing proteins, L-Tryptophan is a critical precursor in the biosynthetic pathways of several key neurotransmitters and hormones that regulate various physiological processes. The most well-known of these is serotonin, a neurotransmitter that is central to mood regulation, sleep, and appetite control. Additionally, L-Tryptophan is involved in the production of melatonin, a hormone that governs circadian rhythms and sleep-wake cycles.


L-Tryptophan (CAS 73-22-3) References

  1. Metabolic engineering for improving L-tryptophan production in Escherichia coli.  |  Niu, H., et al. 2019. J Ind Microbiol Biotechnol. 46: 55-65. PMID: 30426284
  2. Creation of thermostable l-tryptophan dehydrogenase by protein engineering and its application for l-tryptophan quantification.  |  Matsui, D. and Asano, Y. 2019. Anal Biochem. 579: 57-63. PMID: 31100220
  3. Bromination of L-tryptophan in a Fermentative Process With Corynebacterium glutamicum.  |  Veldmann, KH., et al. 2019. Front Bioeng Biotechnol. 7: 219. PMID: 31620432
  4. Polymorphism of l-Tryptophan.  |  Al Rahal, O., et al. 2019. Angew Chem Int Ed Engl. 58: 18788-18792. PMID: 31621998
  5. l-Tryptophan-Induced Vasodilation Is Enhanced in Preeclampsia: Studies on Its Uptake and Metabolism in the Human Placenta.  |  Broekhuizen, M., et al. 2020. Hypertension. 76: 184-194. PMID: 32475317
  6. L-tryptophan: a rational anti-depressant and a natural hypnotic?  |  Boman, B. 1988. Aust N Z J Psychiatry. 22: 83-97. PMID: 3285826
  7. Effects of Methyl Donors on L-Tryptophan Fermentation.  |  Liu, X. 2021. Bioengineered.. PMID: 33522354
  8. Advances and prospects in metabolic engineering of Escherichia coli for L-tryptophan production.  |  Liu, S., et al. 2022. World J Microbiol Biotechnol. 38: 22. PMID: 34989926
  9. Detection of impurities in dietary supplements containing L-tryptophan.  |  Karakawa, S., et al. 2022. Amino Acids. 54: 835-839. PMID: 35043227
  10. Electrochemical determination of L-tryptophan in food samples on graphite electrode prepared from waste batteries.  |  Tasić, ŽZ., et al. 2022. Sci Rep. 12: 5469. PMID: 35361843
  11. l-Serine Biosensor-Controlled Fermentative Production of l-Tryptophan Derivatives by Corynebacterium glutamicum.  |  Ferrer, L., et al. 2022. Biology (Basel). 11: PMID: 35625472
  12. Effects of L-tryptophan on sleepiness and on sleep.  |  Hartmann, E. J Psychiatr Res. 17: 107-13. PMID: 6764927
  13. L-tryptophan and the eosinophilia-myalgia syndrome: current understanding of the etiology and pathogenesis.  |  Varga, J., et al. 1993. J Invest Dermatol. 100: 97S-105S. PMID: 8423409

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Tryptophan, 100 g

sc-280888
100 g
$126.00

L-Tryptophan, 1 kg

sc-280888A
1 kg
$357.00

L-Tryptophan, 5 kg

sc-280888B
5 kg
$1760.00