L-threo-4-Fluoroglutamic acid
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6-Diazo-5-oxo-L-norleucine serves as an influential inhibitor targeting enzymes that utilize glutamine, such as glutaminase and amidotransferases. The compound achieves its inhibitory effect by irreversibly binding to the enzymes′ active sites, thus shutting down critical aspects of glutamine metabolism. This inhibition has broad ramifications on several key cellular processes, particularly those involved in nucleotide and protein synthesis, as well as in energy production. As glutamine plays a central role in cellular metabolism, the interruption of its utilization offers experimental avenue for dissecting the metabolic pathways to cell growth and maintenance. The mechanism by which 6-Diazo-5-oxo-L-norleucine operates provides significant insights into cellular metabolic dependencies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-threo-4-Fluoroglutamic acid, 10 mg | sc-328013 | 10 mg | $235.00 |