Molecular structure of L-Pipecolic Acid, CAS Number: 3105-95-1
L-Pipecolic Acid (CAS 3105-95-1)
Alternate Names:
L-Homoproline; (S)-Piperidine-2-carboxylic acid;
Application:
L-Pipecolic Acid is involved in synaptic transmission in the central nervous system
CAS Number:
3105-95-1
Molecular Weight:
129.16
Molecular Formula:
C6H11NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
L-Pipecolic Acid is a versatile compound that plays a role in multiple metabolic pathways and exerts its influence on various proteins and enzymes. Its interaction with lysine-ketoglutarate reductase, an enzyme for amino acid synthesis, is well-documented. Moreover,L-Pipecolic Acid demonstrates the ability to regulate the activity of key proteins involved in inflammation and oxidative stress, including NF-κB and Nrf2.
L-Pipecolic Acid (CAS 3105-95-1) References
- Biotransformation of L-lysine to L-pipecolic acid catalyzed by L-lysine 6-aminotransferase and pyrroline-5-carboxylate reductase. | Fujii, T., et al. 2002. Biosci Biotechnol Biochem. 66: 622-7. PMID: 12005058
- Enzymatic synthesis of L-pipecolic acid by Delta1-piperideine-2-carboxylate reductase from Pseudomonas putida. | Muramatsu, H., et al. 2006. Biosci Biotechnol Biochem. 70: 2296-8. PMID: 16960365
- Biochemical characterisation of recombinant Streptomyces pristinaespiralis L-lysine cyclodeaminase. | Tsotsou, GE. and Barbirato, F. 2007. Biochimie. 89: 591-604. PMID: 17291665
- Engineering Corynebacterium glutamicum for fast production of L-lysine and L-pipecolic acid. | Pérez-García, F., et al. 2016. Appl Microbiol Biotechnol. 100: 8075-90. PMID: 27345060
- Regulatory effects of the L-lysine metabolites, L-2-aminoadipic acid and L-pipecolic acid, on protein turnover in C2C12 myotubes. | Sato, T., et al. 2016. Biosci Biotechnol Biochem. 80: 2168-2175. PMID: 27427787
- Peroxisomal oxidation of pipecolic acid in the rat. | Kramar, R., et al. 1989. J Clin Chem Clin Biochem. 27: 319-21. PMID: 2760567
- Fermentative production of L-pipecolic acid from glucose and alternative carbon sources. | Pérez-García, F., et al. 2017. Biotechnol J. 12: PMID: 28169491
- Expanding metabolic pathway for de novo biosynthesis of the chiral pharmaceutical intermediate L-pipecolic acid in Escherichia coli. | Ying, H., et al. 2017. Microb Cell Fact. 16: 52. PMID: 28347340
- An economically and environmentally acceptable synthesis of chiral drug intermediate L-pipecolic acid from biomass-derived lysine via artificially engineered microbes. | Cheng, J., et al. 2018. J Ind Microbiol Biotechnol. 45: 405-415. PMID: 29749580
- Intracerebroventricular Injection of L-Pipecolic Acid Exerts Hypnotic Effects Without Activating NMDA Receptors in Neonatal Chicks under Social Isolation-induced Stress. | Shigemura, A., et al. 2020. J Poult Sci. 57: 84-87. PMID: 32174769
- Enzymatic hydroxylation of L-pipecolic acid by L-proline cis-4-hydroxylases and isomers separation. | Lu, F., et al. 2020. Biotechnol Lett. 42: 2607-2617. PMID: 32914260
- In Vitro Fertilisation of Mouse Oocytes in L-Proline and L-Pipecolic Acid Improves Subsequent Development. | Treleaven, T., et al. 2021. Cells. 10: PMID: 34072568
- Depression and anxiety in patients with active ulcerative colitis: crosstalk of gut microbiota, metabolomics and proteomics. | Yuan, X., et al. 2021. Gut Microbes. 13: 1987779. PMID: 34806521
- Enhancement of l-Pipecolic Acid Production by Dynamic Control of Substrates and Multiple Copies of the pipA Gene in the Escherichia coli Genome. | Xu, X., et al. 2022. ACS Synth Biol. 11: 760-769. PMID: 35073050
- Systems metabolic engineering upgrades Corynebacterium glutamicum for selective high-level production of the chiral drug precursor and cell-protective extremolyte L-pipecolic acid. | Pauli, S., et al. 2023. Metab Eng. 77: 100-117. PMID: 36931556
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Pipecolic Acid, 5 g | sc-391179 | 5 g | $234.00 |