Molecular structure of L-NG-Monomethylarginine, Acetate Salt (L-NMMA), CAS Number: 53308-83-1
L-NG-Monomethylarginine, Acetate Salt (L-NMMA) (CAS 53308-83-1)
See product citations (3)
Alternate Names:
Tilarginine Acetate; L-NMMA
Application:
L-NG-Monomethylarginine, Acetate Salt (L-NMMA) is an L-arginine analogue inhibitor of Ca2+-dependent NOS3 (endothelial NOS)
CAS Number:
53308-83-1
Purity:
≥99%
Molecular Weight:
248.28
Molecular Formula:
C7H16N4O2•C2H4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
L-NG-Monomethylarginine, Acetate Salt (L-NMMA), is an analogue of L-arginine that may act to inhibit Ca2+-dependent NOS3 (endothelial NOS) from porcine aorta. In an experiment on porcine aortic rings, L-NMMA was shown to cause contraction and inhibition of the endothelium-dependent relaxation induced by acetylcholine. This compound has also been noted to elicit a dose-dependent increase in mean systemic arterial blood pressure accompanied by bradycardia. Experiments on cat vascular endothelia show that L-NMMA can increase leukocyte adherence and emigration and reduce venular shear rate. Low shear rates have been shown to promote platelet-endothelial and leukocyte-endothelial cell adhesion in mesenteric venules. L-NG-Monomethylarginine, Acetate Salt (L-NMMA) is an inhibitor of NOS1 and NOS2.
L-NG-Monomethylarginine, Acetate Salt (L-NMMA) (CAS 53308-83-1) References
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Inhibitor of:
arginase I, AtNOS1, CAT-1, Enzyme, Furin, GCS-α-1, NOS, NOS1, NOS2, NOS3, Olfr447, and Tas2r103.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-NG-Monomethylarginine, Acetate Salt (L-NMMA), 25 mg | sc-200739 | 25 mg | $90.00 | |||
L-NG-Monomethylarginine, Acetate Salt (L-NMMA), 100 mg | sc-200739A | 100 mg | $260.00 | |||
L-NG-Monomethylarginine, Acetate Salt (L-NMMA), 1 g | sc-200739B | 1 g | $800.00 | |||
L-NG-Monomethylarginine, Acetate Salt (L-NMMA), 100 g | sc-200739C | 100 g | $40378.00 |