Date published: 2025-12-6

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L-Methionine 7-amido-4-methylcoumarin, trifluoroacetate salt (CAS 94367-35-8)

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Application:
CAS Number:
94367-35-8
Molecular Weight:
420.40
Molecular Formula:
C15H18N2O3S•C2HF3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Methionine 7-amido-4-methylcoumarin, trifluoroacetate salt is an important compound in the field of proteomics and enzymology, where it serves as a fluorogenic substrate for assaying protease activity. Specifically, it is used to measure the activity of methionine aminopeptidase enzymes, which play a critical role in the post-translational modification of proteins. The 7-amido-4-methylcoumarin (AMC) moiety releases a fluorescent signal upon enzymatic cleavage, providing a quantifiable means of monitoring the reaction in real-time. This reaction is essential for understanding enzyme kinetics and the specificity of substrate-enzyme interactions. Additionally, this compound finds application in the development of high-throughput screening methods for identifying potential enzyme inhibitors, which are of interest in the study of regulatory mechanisms within cells.


L-Methionine 7-amido-4-methylcoumarin, trifluoroacetate salt (CAS 94367-35-8) References

  1. Changes of enzymes activity and protein profiles caused by high-pressure processing in sea bass (Dicentrarchus labrax) fillets.  |  Teixeira, B., et al. 2013. J Agric Food Chem. 61: 2851-60. PMID: 23425724
  2. Proteolytic activities in fillets of selected underutilized Australian fish species.  |  Ahmed, Z., et al. 2013. Food Chem. 140: 238-44. PMID: 23578639
  3. Activity of endogenous muscle proteases from 4 Australian underutilized fish species as affected by ionic strength, pH, and temperature.  |  Ahmed, Z., et al. 2013. J Food Sci. 78: C1858-64. PMID: 24261640
  4. μ-Calpain oxidation and proteolytic changes on myofibrillar proteins from Coregonus Peled in vitro.  |  Liu, P., et al. 2021. Food Chem. 361: 130100. PMID: 34044215

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Methionine 7-amido-4-methylcoumarin, trifluoroacetate salt, 50 mg

sc-207807
50 mg
$219.00

L-Methionine 7-amido-4-methylcoumarin, trifluoroacetate salt, 250 mg

sc-207807A
250 mg
$719.00

L-Methionine 7-amido-4-methylcoumarin, trifluoroacetate salt, 500 mg

sc-207807B
500 mg
$1229.00

L-Methionine 7-amido-4-methylcoumarin, trifluoroacetate salt, 1 g

sc-207807C
1 g
$2147.00