Date published: 2025-9-27

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L-Lysine (CAS 56-87-1)

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Alternate Names:
(2S)-2,6-diaminohexanoic acid
Application:
L-Lysine is a moderate serotonin antagonist and essential amino acid
CAS Number:
56-87-1
Purity:
≥98%
Molecular Weight:
146.19
Molecular Formula:
C6H14N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Lysine is an essential alpha-amino acid, which is encoded by the codons AAA and AAG. Studies suggest that L-Lysine is a key building block in protein synthesis in which it acts as a base. The poly L-Lysine form can be used to suppress prion propagation in mouse models. This amino acid is often post-translationally modified producing analogues that serve different functions. These modifications include acetylation, methylation, ubiquitination, sumoylation, neddylation, biotinylation, pupylation and carboxylation. Furthermore, L-Lysine is a moderate serotonin antagonist, which suppresses its release from SR-4 (5-HT4) receptors.


L-Lysine (CAS 56-87-1) References

  1. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats.  |  Smriga, M. and Torii, K. 2003. Proc Natl Acad Sci U S A. 100: 15370-5. PMID: 14676321
  2. The suppression of prion propagation using poly-L-lysine by targeting plasminogen that stimulates prion protein conversion.  |  Ryou, C., et al. 2011. Biomaterials. 32: 3141-9. PMID: 21288569
  3. L-Lysine-α-Oxidase: Acidovorax citrulli Bacterium Inhibitor.  |  Smirnova, IP., et al. 2018. Bull Exp Biol Med. 164: 459-461. PMID: 29504100
  4. L-lysine production improvement: a review of the state of the art and patent landscape focusing on strain development and fermentation technologies.  |  Félix, FKDC., et al. 2019. Crit Rev Biotechnol. 39: 1031-1055. PMID: 31544527
  5. Comprehensive Safety Assessment of l-Lysine Supplementation from Clinical Studies: A Systematic Review.  |  Hayamizu, K., et al. 2020. J Nutr. 150: 2561S-2569S. PMID: 33000161
  6. L-lysine therapy to control the clinical evolution of pityriasis rosea: Clinical case report and literature review.  |  Pedrazini, MC. and Groppo, FC. 2021. Dermatol Ther. 34: e14679. PMID: 33326128
  7. l-Arginine and l-Lysine Alleviate Myosin from Oxidation: Their Role in Maintaining Myosin's Emulsifying Properties.  |  Zhang, D., et al. 2021. J Agric Food Chem. 69: 3189-3198. PMID: 33496584
  8. A comprehensive review of methods for determination of l-lysine with detailed description of biosensors.  |  Pundir, CS., et al. 2021. Int J Biol Macromol. 186: 445-461. PMID: 34229019
  9. Engineered Halomonas spp. for production of l-Lysine and cadaverine.  |  Zhao, C., et al. 2022. Bioresour Technol. 349: 126865. PMID: 35183730
  10. Poly(ε-L-lysine) and poly(L-diaminopropionic acid) co-produced from spent mushroom substrate fermentation: potential use as food preservatives.  |  Wang, M. and Rong, C. 2022. Bioengineered. 13: 5892-5902. PMID: 35188864
  11. l-Lysine-Based Gelators for the Formation of Oleogels in Four Vegetable Oils.  |  Li, Q., et al. 2022. Molecules. 27: PMID: 35209157
  12. A Novel Efficient L-Lysine Exporter Identified by Functional Metagenomics.  |  Malla, S., et al. 2022. Front Microbiol. 13: 855736. PMID: 35495724
  13. Effect of L-arginine and L-Lysine HCl ratio on growth performance and ileum morphology of native chickens aged 2-14 weeks.  |  Lisnahan, CV., et al. 2022. Vet World. 15: 1365-1372. PMID: 35765480
  14. Co-production of l-Lysine and Heterologous Squalene in CRISPR/dCas9-Assisted Corynebacterium glutamicum.  |  Park, J. and Woo, HM. 2022. J Agric Food Chem. 70: 14755-14760. PMID: 36374274
  15. Construction of L-lysine-, L-threonine-, and L-isoleucine-overproducing strains of Corynebacterium glutamicum.  |  Sahm, H., et al. 1996. Ann N Y Acad Sci. 782: 25-39. PMID: 8659901

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Lysine, 25 g

sc-207804
25 g
$93.00

L-Lysine, 100 g

sc-207804A
100 g
$258.00

L-Lysine, 1 kg

sc-207804B
1 kg
$519.00