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L-Leucine 7-amido-4-methylcoumarin (CAS 66447-31-2)

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Alternate Names:
H-Leu-AMC; L-Leu-AMC
Application:
L-Leucine 7-amido-4-methylcoumarin is a fluorogenic substrate
CAS Number:
66447-31-2
Molecular Weight:
288.37
Molecular Formula:
C16H20N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Leucine 7-amido-4-methylcoumarin is a sensitive fluorogenic substrate for LAP3 (leucine aminopeptidase) and aminopeptidase M.


L-Leucine 7-amido-4-methylcoumarin (CAS 66447-31-2) References

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  2. Leucine Aminopeptidase in Eggs of the Soybean Cyst Nematode Heterodera glycines.  |  Tefft, PM. and Bone, LW. 1985. J Nematol. 17: 270-4. PMID: 19294093
  3. RNA interference targeting leucine aminopeptidase blocks hatching of Schistosoma mansoni eggs.  |  Rinaldi, G., et al. 2009. Mol Biochem Parasitol. 167: 118-26. PMID: 19463860
  4. Skeletocutins M-Q: biologically active compounds from the fruiting bodies of the basidiomycete Skeletocutis sp. collected in Africa.  |  Cheng, T., et al. 2019. Beilstein J Org Chem. 15: 2782-2789. PMID: 31807212
  5. Ectomycorrhizal and non-mycorrhizal rhizosphere fungi increase root-derived C input to soil and modify enzyme activities: A 14 C pulse labelling of Picea abies seedlings.  |  Zhou, J., et al. 2022. Plant Cell Environ. 45: 3122-3133. PMID: 35909089
  6. Effects of intermittent flow on biofilms are driven by stream characteristics rather than history of intermittency.  |  Coulson, LE., et al. 2022. Sci Total Environ. 849: 157809. PMID: 35934041
  7. Genomic and transcriptomic characterization of the Collimonas quorum sensing genes and regulon.  |  Uroz, S., et al. 2022. FEMS Microbiol Ecol. 98: PMID: 36040340
  8. Structural and biochemical insights into the association between ERAP1 polymorphism and autoimmune diseases.  |  Liu, S., et al. 2022. Biochem Biophys Res Commun. 632: 189-194. PMID: 36228519
  9. Nutrient recovery and changes in enzyme activity during vermicomposting of hydrolysed chicken feather residue.  |  Dume, B., et al. 2022. Environ Technol. 1-15. PMID: 36368925
  10. Purification and characterization of an aminopeptidase from Plasmodium falciparum.  |  Vander Jagt, DL., et al. 1984. Mol Biochem Parasitol. 10: 45-54. PMID: 6363922
  11. Subcellular localisation of leucine aminopeptidase in human polymorphonuclear leukocytes.  |  Smith, GP., et al. 1983. Biochim Biophys Acta. 728: 222-7. PMID: 6830778
  12. Localization of leucine aminopeptidase and vitamin B-12 binding protein in rabbit peripheral blood polymorphonuclear leukocytes.  |  Smith, GP., et al. 1982. Biochim Biophys Acta. 719: 532-8. PMID: 7150659

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Leucine 7-amido-4-methylcoumarin, 100 mg

sc-300884
100 mg
$310.00

L-Leucine 7-amido-4-methylcoumarin, 250 mg

sc-300884A
250 mg
$650.00