Molecular structure of L,L-Dityrosine dihydrochloride, CAS Number: 221308-01-6
L,L-Dityrosine dihydrochloride (CAS 221308-01-6)
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Alternate Names:
Bityrosine Dihydrochloride; Dityrosine Dihydrochloride; o,o-Dityrosine Dihydrochloride
CAS Number:
221308-01-6
Molecular Weight:
433.28
Molecular Formula:
C18H22Cl2N2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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L,L-Dityrosine dihydrochloride has found utility as a crosslinking agent to enhance the stability of proteins and peptides. Similarly, in materials science, it has been employed as a fundamental component for synthesizing novel materials endowed with exceptional properties. The mechanism of action is believed to involve the covalent bonding between two tyrosine residues, leading to the formation of a dimeric structure that surpasses the stability of individual tyrosine residues. Importantly, the formation of L,L-Dityrosine dihydrochloride has been observed to rely on the presence of reactive oxygen species, such as hydrogen peroxide or superoxide.
L,L-Dityrosine dihydrochloride (CAS 221308-01-6) References
- Haem-assisted dityrosine-cross-linking of fibrinogen under non-thermal plasma exposure: one important mechanism of facilitated blood coagulation. | Ke, Z. and Huang, Q. 2016. Sci Rep. 6: 26982. PMID: 27229173
- The C-terminal cytosolic domain of the human zinc transporter ZnT8 and its diabetes risk variant. | Parsons, DS., et al. 2018. FEBS J. 285: 1237-1250. PMID: 29430817
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L,L-Dityrosine dihydrochloride, 0.5 mg | sc-497286 | 0.5 mg | $421.00 |