Molecular structure of L-Isoleucine, CAS Number: 73-32-5
L-Isoleucine (CAS 73-32-5)
Alternate Names:
2S,3S-Isoleucine; 2-Amino-3-methylvaleric acid
Application:
L-Isoleucine is a branched chain amino acid
CAS Number:
73-32-5
Purity:
≥98%
Molecular Weight:
131.18
Molecular Formula:
C6H13NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
L-Isoleucine is an essential amino acid. It is one of the three branched-chain amino acids (BCAAs) and is present in all proteins. This amino acid is for the production of hemoglobin, which transports oxygen in the blood. It also plays a vital role in muscle growth and repair and is necessary for energy production. In the realm of scientific research, L-Isoleucine finds applications in both in vivo and in vitro experiments. It participates in various biochemical processes, including protein and hormone synthesis, blood sugar regulation, and energy production. Furthermore, it plays a role in the creation of hemoglobin, the oxygen-carrying molecule in the bloodstream.
L-Isoleucine (CAS 73-32-5) References
- Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase. | Fukai, S., et al. 2000. Cell. 103: 793-803. PMID: 11114335
- Evidence for a negative-feedback mechanism in the biosynthesis of isoleucine. | UMBARGER, HE. 1956. Science. 123: 848. PMID: 13324101
- The feedback control mechanisms of biosynthetic L-threonine deaminase by L-isoleucine. | CHANGEUX, JP. 1961. Cold Spring Harb Symp Quant Biol. 26: 313-8. PMID: 13878122
- l-Isoleucine Production with Corynebacterium glutamicum: Further Flux Increase and Limitation of Export. | Morbach, S., et al. 1996. Appl Environ Microbiol. 62: 4345-51. PMID: 16535457
- Acute and chronic treatment of L-isoleucine ameliorates glucose metabolism in glucose-intolerant and diabetic mice. | Ikehara, O., et al. 2008. Biol Pharm Bull. 31: 469-72. PMID: 18310912
- A novel l-isoleucine hydroxylating enzyme, l-isoleucine dioxygenase from Bacillus thuringiensis, produces (2S,3R,4S)-4-hydroxyisoleucine. | Kodera, T., et al. 2009. Biochem Biophys Res Commun. 390: 506-10. PMID: 19850012
- Co-expression of feedback-resistant threonine dehydratase and acetohydroxy acid synthase increase L-isoleucine production in Corynebacterium glutamicum. | Yin, L., et al. 2012. Metab Eng. 14: 542-50. PMID: 22771937
- Zn(2+) and L-isoleucine induce the expressions of porcine β-defensins in IPEC-J2 cells. | Mao, X., et al. 2013. Mol Biol Rep. 40: 1547-52. PMID: 23065293
- Rational design of Escherichia coli for L-isoleucine production. | Park, JH., et al. 2012. ACS Synth Biol. 1: 532-40. PMID: 23656230
- Attenuating l-lysine production by deletion of ddh and lysE and their effect on l-threonine and l-isoleucine production in Corynebacterium glutamicum. | Dong, X., et al. 2016. Enzyme Microb Technol. 93-94: 70-78. PMID: 27702487
- Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) co-produced with L-isoleucine in Corynebacterium glutamicum WM001. | Ma, W., et al. 2018. Microb Cell Fact. 17: 93. PMID: 29907151
- L-isoleucine and L-leucine: tumor promoters of bladder cancer in rats. | Nishio, Y., et al. 1986. Science. 231: 843-5. PMID: 3945812
- Construction of L-lysine-, L-threonine-, and L-isoleucine-overproducing strains of Corynebacterium glutamicum. | Sahm, H., et al. 1996. Ann N Y Acad Sci. 782: 25-39. PMID: 8659901
Inhibitor of:
SLC7A9.Activator of:
5430416O09Rik, BAT2, BCKDE1A, BCKDHB, EG628456, GnT-IVH, GPR142, GPR41, LeuRS, NSUN5, PAT2, PCCA, Pepsin A, QRSL1, SLC38A6, SLC6A15, SLC6A19, SLC7A10, SLC7A9, ValRS, and YLAT1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Isoleucine, 25 g | sc-396706 | 25 g | $24.00 | |||
L-Isoleucine, 100 g | sc-396706A | 100 g | $118.00 |