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L-Homoserine (CAS 672-15-1)

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Alternate Names:
(S)-2-Amino-4-hydroxybutyric acid, Hse
CAS Number:
672-15-1
Purity:
≥98%
Molecular Weight:
119.12
Molecular Formula:
C4H9NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Homoserine is a non-proteinogenic amino acid that is present in various organisms, including plants, animals, and bacteria. Unlike the standard amino acids used for protein synthesis, L-Homoserine does not contribute directly to protein formation. However, it plays significant roles in several biochemical processes. L-Homoserine is involved in the synthesis of certain vitamins and hormones, highlighting its importance in cellular metabolism. It is also believed to act as an allosteric modulator of specific enzymes, such as homoserine transaminase, influencing their activity and regulation. L-Homoserine serves as a cofactor in the synthesis of certain vitamins and hormones, further emphasizing its relevance in metabolic pathways.


L-Homoserine (CAS 672-15-1) References

  1. Effect of l-Homoserine on the Growth of Mycobacterium tuberculosis.  |  O'barr, TP. and Everett, KA. 1971. Infect Immun. 3: 328-32. PMID: 16557973
  2. Dietary L-homoserine spares threonine in chicks.  |  Bryant, KI., et al. 2009. J Nutr. 139: 1298-302. PMID: 19474159
  3. Increasing L-homoserine production in Escherichia coli by engineering the central metabolic pathways.  |  Liu, M., et al. 2020. J Biotechnol. 314-315: 1-7. PMID: 32251699
  4. Multiplex Design of the Metabolic Network for Production of l-Homoserine in Escherichia coli.  |  Liu, P., et al. 2020. Appl Environ Microbiol. 86: PMID: 32801175
  5. High-level production of l-homoserine using a non-induced, non-auxotrophic Escherichia coli chassis through metabolic engineering.  |  Zhang, Y., et al. 2021. Bioresour Technol. 327: 124814. PMID: 33592493
  6. [Metabolic engineering of Escherichia coli for L-homoserine production].  |  Zhang, B., et al. 2021. Sheng Wu Gong Cheng Xue Bao. 37: 1287-1297. PMID: 33973442
  7. Highly efficient production of L-homoserine in Escherichia coli by engineering a redox balance route.  |  Mu, Q., et al. 2021. Metab Eng. 67: 321-329. PMID: 34329706
  8. Development of a nonauxotrophic L-homoserine hyperproducer in Escherichia coli by systems metabolic engineering.  |  Cai, M., et al. 2022. Metab Eng. 73: 270-279. PMID: 35961600
  9. YgeA is involved in L- and D-homoserine metabolism in Escherichia coli.  |  Miyamoto, T., et al. 2022. FEMS Microbiol Lett. 369: PMID: 36214408
  10. Engineering Escherichia coli for l-homoserine production.  |  Sun, BY., et al. 2023. J Basic Microbiol. 63: 168-178. PMID: 36284486
  11. Dual-channel glycolysis balances cofactor supply for l-homoserine biosynthesis in Corynebacterium glutamicum.  |  Li, N., et al. 2023. Bioresour Technol. 369: 128473. PMID: 36509305
  12. Toxic effect and inability of L-homoserine to be a nitrogen source for growth of Escherichia coli resolved by a combination of in vivo evolution engineering and omics analyses.  |  Alkim, C., et al. 2022. Front Microbiol. 13: 1051425. PMID: 36583047
  13. [Advances in the biosynthesis of L-homoserine and its derivatives by metabolic engineering of Escherichia coli].  |  Niu, K., et al. 2022. Sheng Wu Gong Cheng Xue Bao. 38: 4385-4402. PMID: 36593184
  14. Homoserine kinase of Escherichia coli: kinetic mechanism and inhibition by L-aspartate semialdehyde.  |  Shames, SL. and Wedler, FC. 1984. Arch Biochem Biophys. 235: 359-70. PMID: 6097184

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Homoserine, 10 mg

sc-207802
10 mg
$20.00

L-Homoserine, 250 mg

sc-207802A
250 mg
$101.00