L-Homocitrulline (CAS 1190-49-4)
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L-Homocitrulline is a non-proteinogenic amino acid, which means it does not naturally incorporate into proteins during biosynthesis. Structurally, it is similar to the amino acid citrulline, but with an additional methylene (-CH2-) group in its side chain. This modification extends the carbon chain length between the amino group and the carbonyl group, altering its chemical properties compared to citrulline. L-Homocitrulline is particularly significant in medical and biochemical research due to its role as a biomarker for certain metabolic disorders. L-Homocitrulline plays a role in cellular metabolism as a key intermediate in the urea cycle. L-Homocitrulline interacts with enzymes such as ornithine transcarbamylase and argininosuccinate synthetase, facilitating the production of citrulline and arginine, which are essential for the detoxification of ammonia.
L-Homocitrulline (CAS 1190-49-4) References
- Serum metabolomic profiling reveals an increase in homocitrulline in Chinese patients with nonalcoholic fatty liver disease: a retrospective study. | Yang, Y., et al. 2021. PeerJ. 9: e11346. PMID: 33987020
- Prediction of response and adverse drug reaction of pemetrexed plus platinum-based chemotherapy in lung adenocarcinoma by serum metabolomic profiling. | Gong, WJ., et al. 2022. Transl Oncol. 19: 101393. PMID: 35290920
- Integrative network analysis revealed the molecular function of folic acid on immunological enhancement in a sheep model. | Wang, B., et al. 2022. Front Immunol. 13: 913854. PMID: 36032143
- Long-Term Dietary Lycium ruthenicum Murr. Anthocyanins Intake Alleviated Oxidative Stress-Mediated Aging-Related Liver Injury and Abnormal Amino Acid Metabolism. | Chen, S., et al. 2022. Foods. 11: PMID: 36359989
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Homocitrulline, 100 mg | sc-269298 | 100 mg | $71.00 | |||
L-Homocitrulline, 1 g | sc-269298A | 1 g | $245.00 | |||
L-Homocitrulline, 10 g | sc-269298B | 10 g | $480.00 | |||
L-Homocitrulline, 25 g | sc-269298C | 25 g | $1076.00 |