L-Histidine (CAS 71-00-1)
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L-Histidine, identified by the symbol H, is an essential amino acid that is indispensable for its role as a building block of proteins, given its status among the 22 proteinogenic amino acids. This amino acid is foundational in the formation of histamine and is a key constituent of carnosine, contributing to numerous biochemical operations. It is characterized as a solid, soluble organic compound with a moderate level of acidity, and is widespread across various tissues and biofluids such as feces, urine, sweat, and blood, predominantly located within the cytoplasm and mitochondria of cells. L-Histidine is universal among eukaryotes, from yeast to humans, playing a role in the biosynthesis of compounds like L-carnosine and homocarnosine, and in the chelation of metal ions, which is vital for the transport of copper and the function of enzymes and other macromolecules. Its involvement in the metabolism into urocanic acid and its presence in several metabolic pathways highlight its extensive role in biochemical processes.
L-Histidine (CAS 71-00-1) References
- L-histidine is a beneficial adjuvant for antiepileptic drugs against maximal electroshock-induced seizures in mice. | Kamiński, RM., et al. 2004. Amino Acids. 26: 85-9. PMID: 14752621
- L-histidine inhibits biofilm formation and FLO11-associated phenotypes in Saccharomyces cerevisiae flor yeasts. | Bou Zeidan, M., et al. 2014. PLoS One. 9: e112141. PMID: 25369456
- A novel label-free colorimetric detection of l-histidine using Cu2+-modulated G-quadruplex-based DNAzymes. | Gu, P., et al. 2018. Spectrochim Acta A Mol Biomol Spectrosc. 203: 195-200. PMID: 29864643
- Colorimetric detection of L-histidine based on the target-triggered self-cleavage of swing-structured DNA duplex-induced aggregation of gold nanoparticles. | Jiao, Y., et al. 2018. Mikrochim Acta. 185: 452. PMID: 30209628
- Development of a novel l-histidine assay method using histamine dehydrogenase and a stable mutant of histidine decarboxylase. | Yamaguchi, H., et al. 2019. Anal Biochem. 570: 13-20. PMID: 30586560
- Electron Spin-Polarization Dependent Damage to Chiral Amino Acid l-Histidine. | Schaible, MJ., et al. 2020. J Phys Chem Lett. 11: 10182-10187. PMID: 33200930
- Identification of l-histidine oxidase activity in Achromobacter sp. TPU 5009 for l-histidine determination. | Matsui, D., et al. 2021. J Biosci Bioeng. 131: 469-474. PMID: 33487551
- Heat Capacities of l-Histidine, l-Phenylalanine, l-Proline, l-Tryptophan and l-Tyrosine. | Pokorný, V., et al. 2021. Molecules. 26: PMID: 34299573
- Gut Microbiota-Derived l-Histidine/Imidazole Propionate Axis Fights against the Radiation-Induced Cardiopulmonary Injury. | Chen, Z., et al. 2021. Int J Mol Sci. 22: PMID: 34768867
- Effects of β-alanine and L-histidine supplementation on carnosine contents in and quality and secondary structure of proteins in slow-growing Korat chicken meat. | Suwanvichanee, C., et al. 2022. Poult Sci. 101: 101776. PMID: 35303689
- A near-infrared fluorescence capillary imprinted sensor for chiral recognition and sensitive detection of l-histidine. | Tang, S., et al. 2022. Anal Chim Acta. 1206: 339794. PMID: 35473870
- Chiral 2D organic-inorganic hybrid perovskites based on L-histidine. | Sirenko, VY., et al. 2022. Dalton Trans. 51: 16536-16544. PMID: 36254897
- Entropically-Driven Co-assembly of l-Histidine and l-Phenylalanine to Form Supramolecular Materials. | Tiwari, OS., et al. 2023. ACS Nano. 17: 3506-3517. PMID: 36745579
- Combinatorial Protein Engineering and Metabolic Engineering for Efficient Synthesis of l-Histidine in Corynebacterium glutamicum. | Chai, M., et al. 2023. ACS Synth Biol. 12: 1275-1286. PMID: 37027231
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Histidine, 25 g | sc-394101 | 25 g | $53.00 | |||
L-Histidine, 100 g | sc-394101A | 100 g | $82.00 | |||
L-Histidine, 250 g | sc-394101B | 250 g | $185.00 | |||
L-Histidine, 500 g | sc-394101C | 500 g | $200.00 | |||
L-Histidine, 1 kg | sc-394101D | 1 kg | $332.00 |