Date published: 2025-10-14

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L-Glutamine-amide-15N (CAS 59681-32-2)

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Alternate Names:
Acustasin-15N; Aesgen 14-15N; Cebrogen-15N
Application:
L-Glutamine-amide-15N is a labelled L-Glutamine
CAS Number:
59681-32-2
Molecular Weight:
147.14
Molecular Formula:
C5H10(15N)NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Glutamine-amide-15N is a labelled L-Glutamine (sc-391013). L-Glutamine is an essential amino acid that is a component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use. It serves as a versatile amino acid derivative extensively employed in diverse scientific research applications. This isotopically labeled form of the naturally occurring amino acid L-glutamine is an invaluable tool for studying proteins and enzymes. In the realm of biochemical and physiological studies, L-Glutamine-amide-15N acts as a chemical probe, facilitating investigations into the structure, function, and dynamics of proteins and enzymes, as well as their interactions with other molecules. Its utility extends to various laboratory experiments, encompassing protein purification, enzyme kinetics, and the exploration of metabolic pathways. By incorporating L-Glutamine-amide-15N into proteins and enzymes, the presence of 15N atoms enables comprehensive exploration of their structure, function, dynamics, and interactions with precision. Consequently, L-Glutamine-amide-15N plays a fundamental role in enhancing our understanding of these vital biomolecules and their behavior in scientific research.


L-Glutamine-amide-15N (CAS 59681-32-2) References

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  3. Staphylococcus aureus Infection Reduces Nutrition Uptake and Nucleotide Biosynthesis in a Human Airway Epithelial Cell Line.  |  Gierok, P., et al. 2016. Metabolites. 6: PMID: 27834866
  4. Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer.  |  Brown, KK., et al. 2017. Cancer Discov. 7: 391-399. PMID: 28255083
  5. A Rapid Array-Based Approach to N-Glycan Profiling of Cultured Cells.  |  Angel, PM., et al. 2019. J Proteome Res. 18: 3630-3639. PMID: 31535553
  6. Metabolic Profiling from an Asymptomatic Ferret Model of SARS-CoV-2 Infection.  |  Beale, DJ., et al. 2021. Metabolites. 11: PMID: 34069591
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  8. Inhibition of de novo pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer.  |  Phan, T., et al. 2021. Int J Biol Sci. 17: 2240-2251. PMID: 34239352
  9. Thyroid hormone regulates glutamine metabolism and anaplerotic fluxes by inducing mitochondrial glutamate aminotransferase GPT2.  |  Cicatiello, AG., et al. 2022. Cell Rep. 38: 110409. PMID: 35196498
  10. Glutamine-dependent signaling controls pluripotent stem cell fate.  |  Lu, V., et al. 2022. Dev Cell. 57: 610-623.e8. PMID: 35216682
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Glutamine-amide-15N, 1 g

sc-396181
1 g
$476.00