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L-Glutamic acid γ-(7-amido-4-methylcoumarin) (CAS 72669-53-5)

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Alternate Names:
H-Glu(AMC)-OH
Application:
L-Glutamic acid γ-(7-amido-4-methylcoumarin) is a substrate for aminopeptidase a
CAS Number:
72669-53-5
Molecular Weight:
304.30
Molecular Formula:
C15H16N2O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Glutamic acid gamma-(7-amido-4-methylcoumarin) is a naturally occurring monosaccharide found in the cell walls of bacteria, fungi, and other organisms. It is a substrate for aminopeptidase or the assay of gamma-glutamyl transferase producing a blue fluorescent solution upon cleavage. It is also used in the synthesis of chitin, a polysaccharide found in the exoskeletons of insects and crustaceans. Scientific research employs this compound to study the structure and function of proteins, enzymes, nucleic acids, and cell membranes.


L-Glutamic acid γ-(7-amido-4-methylcoumarin) (CAS 72669-53-5) References

  1. Purified gamma-glutamyl transpeptidases from tomato exhibit high affinity for glutathione and glutathione S-conjugates.  |  Martin, MN. and Slovin, JP. 2000. Plant Physiol. 122: 1417-26. PMID: 10759537
  2. Characterization of biotransformation enzyme activities in primary rat proximal tubular cells.  |  Schaaf, GJ., et al. 2001. Chem Biol Interact. 134: 167-90. PMID: 11311212
  3. Assay of apical membrane enzymes based on fluorogenic substrates.  |  Blackmon, DL., et al. 1992. Anal Biochem. 200: 352-8. PMID: 1352946
  4. Probing the donor and acceptor substrate specificity of the γ-glutamyl transpeptidase.  |  Hu, X., et al. 2012. Biochemistry. 51: 1199-212. PMID: 22257032
  5. Multiplex Optical Urinalysis for Early Detection of Drug-Induced Kidney Injury.  |  Cheng, P., et al. 2020. Anal Chem. 92: 6166-6172. PMID: 32241110

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Glutamic acid γ-(7-amido-4-methylcoumarin), 50 mg

sc-281542
50 mg
$157.00

L-Glutamic acid γ-(7-amido-4-methylcoumarin), 100 mg

sc-281542A
100 mg
$221.00