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L-Glutamic acid diethyl ester hydrochloride (CAS 1118-89-4)

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Application:
L-Glutamic acid diethyl ester hydrochloride is the diethyl ester of glutamic acid
CAS Number:
1118-89-4
Molecular Weight:
239.70
Molecular Formula:
C9H17NO4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Glutamic acid diethyl ester hydrochloride is a compound that functions as a precursor in the synthesis of various organic compounds. It acts as an intermediate in the production of agrochemicals, and other fine chemicals. The compound′s mechanism of action involves participating in esterification reactions, where it undergoes chemical transformations to form ester bonds with other molecules. This process allows for the creation of new compounds with specific chemical properties and functionalities. In a development setting, L-Glutamic acid diethyl ester hydrochloride serves as a building block for the synthesis of diverse chemical products, contributing to the advancement of various scientific fields. Its role in chemical synthesis involves its ability to undergo specific reactions, leading to the formation of desired products with tailored properties.


L-Glutamic acid diethyl ester hydrochloride (CAS 1118-89-4) References

  1. Protease-catalyzed regioselective polymerization and copolymerization of glutamic acid diethyl ester.  |  Uyama, H., et al. 2002. Biomacromolecules. 3: 318-23. PMID: 11888318
  2. Design, synthesis, and biological evaluation of classical and nonclassical 2-amino-4-oxo-5-substituted-6-methylpyrrolo[3,2-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors.  |  Gangjee, A., et al. 2008. J Med Chem. 51: 68-76. PMID: 18072727
  3. Potent dual thymidylate synthase and dihydrofolate reductase inhibitors: classical and nonclassical 2-amino-4-oxo-5-arylthio-substituted-6-methylthieno[2,3-d]pyrimidine antifolates.  |  Gangjee, A., et al. 2008. J Med Chem. 51: 5789-97. PMID: 18800768
  4. Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents.  |  Gangjee, A., et al. 2009. J Med Chem. 52: 4892-902. PMID: 19719239
  5. Self-assembly and morphology control of new L-glutamic acid-based amphiphilic random copolymers: giant vesicles, vesicles, spheres, and honeycomb film.  |  Zhu, X. and Liu, M. 2011. Langmuir. 27: 12844-50. PMID: 21942537
  6. Recent advances in chemoenzymatic peptide syntheses.  |  Yazawa, K. and Numata, K. 2014. Molecules. 19: 13755-74. PMID: 25191871
  7. Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.  |  Golani, LK., et al. 2016. J Med Chem. 59: 7856-76. PMID: 27458733
  8. Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3- d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis.  |  Ravindra, M., et al. 2018. J Med Chem. 61: 2027-2040. PMID: 29425443
  9. Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.  |  Ravindra, M., et al. 2018. J Med Chem. 61: 4228-4248. PMID: 29701475
  10. Synthesis and supramolecular self-assembly of glutamic acid-based squaramides.  |  Alegre-Requena, JV., et al. 2018. Beilstein J Org Chem. 14: 2065-2073. PMID: 30202459
  11. Papain-Catalyzed Synthesis of Polyglutamate Containing a Nylon Monomer Unit.  |  Yazawa, K. and Numata, K. 2016. Polymers (Basel). 8: PMID: 30979286
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  13. Cortical pyramidal tract interneurones and their sensitivity to L-glutamic acid.  |  Stone, TW. 1973. J Physiol. 233: 211-25. PMID: 4357199

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Glutamic acid diethyl ester hydrochloride, 5 g

sc-255241
5 g
$37.00

L-Glutamic acid diethyl ester hydrochloride, 10 g

sc-255241A
10 g
$163.00