Molecular structure of L-Glutamic acid di-tert-butyl ester hydrochloride, CAS Number: 32677-01-3
L-Glutamic acid di-tert-butyl ester hydrochloride (CAS 32677-01-3)
CAS Number:
32677-01-3
Molecular Weight:
295.80
Molecular Formula:
C13H25NO4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
L-Glutamic acid di-tert-butyl ester hydrochloride, known as GLU-DTB, is a versatile organic compound widely applied in the biotechnological, and chemical industries. L-Glutamic acid di-tert-butyl ester hydrochloride is a white crystalline powder, readily soluble in water, alcohols, and various organic solvents. In scientific research, L-Glutamic acid di-tert-butyl ester hydrochloride finds diverse utility. It serves as a component in the synthesis of peptides and other biologically active molecules. Additionally, it has been instrumental in the preparation of peptide libraries employed in high-throughput screening methods.
L-Glutamic acid di-tert-butyl ester hydrochloride (CAS 32677-01-3) References
- Synthesis of macrocyclic analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE). | Harris, PW. and Brimble, MA. 2006. Org Biomol Chem. 4: 2696-709. PMID: 16826294
- Synthesis, characterization, and biological evaluation of poly(L-γ-glutamyl-glutamine)- paclitaxel nanoconjugate. | Van, S., et al. 2010. Int J Nanomedicine. 5: 825-37. PMID: 21042550
- Synthesis, characterization, and in vivo efficacy evaluation of PGG-docetaxel conjugate for potential cancer chemotherapy. | Yang, D., et al. 2012. Int J Nanomedicine. 7: 581-9. PMID: 22334784
- Targeted poly (L-γ-glutamyl glutamine) nanoparticles of docetaxel against folate over-expressed breast cancer cells. | Tavassolian, F., et al. 2014. Int J Pharm. 467: 123-38. PMID: 24680951
- Novel β- and γ-Amino Acid-Derived Inhibitors of Prostate-Specific Membrane Antigen. | Kim, K., et al. 2020. J Med Chem. 63: 3261-3273. PMID: 32097010
- Structure-activity relationship studies of prostate-specific membrane antigen (PSMA) inhibitors derived from α-amino acid with (S)- or (R)-configuration at P1' region. | Kwon, H., et al. 2020. Bioorg Chem. 104: 104304. PMID: 33011530
- Lysosomotropic agents. 7. Broad-spectrum antifungal activity of lysosomotropic detergents. | Firestone, RA., et al. 1987. J Med Chem. 30: 1519-21. PMID: 3302260
- Synthesis, computational docking and biological evaluation of celastrol derivatives as dual inhibitors of SERCA and P-glycoprotein in cancer therapy. | Coghi, P., et al. 2021. Eur J Med Chem. 224: 113676. PMID: 34256125
- Discovery of an Amino Acid-Modified Near-Infrared Aza-BODIPY Photosensitizer as an Immune Initiator for Potent Photodynamic Therapy in Melanoma. | Yu, Z., et al. 2022. J Med Chem. 65: 3616-3631. PMID: 35152702
- Synthesis of 5-chloro-5,8-dideaza analogues of folic acid and aminopterin targeted for colon adenocarcinoma. | Hynes, JB., et al. 1987. J Med Chem. 30: 1515-9. PMID: 3612694
- Facile Synthesis of dl-4,4-Difluoroornithine, dl-4,4-Difluoroglutamine, and γ-dl-4,4-Difluoroglutamyl-Containing Peptides: Regiospecific Addition of Nucleophiles to N-Cbz-di-tert-butyl-dl-4,4-difluoroglutamate | Takashi Tsukamoto and James K. Coward. 1996,. J. Org. Chem. 61, 7,: 2497–2500.
- A Chemoselective and Modular Post-Synthetic Multi-Functionalization of NHC–Platinum Complexes | and Georges Dahm, Etienne Borré, Gilles Guichard, Stéphane Bellemin-Laponnaz. April 2015. European Journal of Inorganic Chemistry. Volume2015, Issue10: Pages 1665-1668.
- Strategies for the synthesis of HBGl3, a glutamic acid derived ligand bearing phenolic and azacarboxylate donor groups at the nitrogen atom | RS Mulla, MT Walden, DS Yufit, T Desa, E Lurie-Luke… - Tetrahedron, 2017 - Elsevier. 9 November 2017,. Tetrahedron. Volume 73, Issue 45,: Pages 6410-6420.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Glutamic acid di-tert-butyl ester hydrochloride, 1 g | sc-250216 | 1 g | $60.00 |