L-Glutamic acid beta-naphthylamide (CAS 635-86-9)
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L-Glutamic acid beta-naphthylamide is a synthetic compound that has found extensive use in scientific research to explore various biochemical and physiological processes. Researchers have employed GAN in diverse applications, including the investigation of enzyme activity, protein folding, and neurotransmitter release. Moreover, L-Glutamic acid beta-naphthylamide acts as a substrate for the enzyme gamma-glutamyl transpeptidase (GGT), which plays a role in the metabolism of glutathione, a major antioxidant in the body. In particular, L-Glutamic acid beta-naphthylamide has proven valuable as a probe to study the conformational changes of proteins. Its ability to bind to hydrophobic pockets within proteins induces structural modifications. GGT cleaves the amide bond between the glutamic acid and beta-naphthylamine components in L-Glutamic acid beta-naphthylamide, releasing beta-naphthylamine, which can be detected using a spectrophotometric assay.
L-Glutamic acid beta-naphthylamide (CAS 635-86-9) References
- Purification by affinity chromatography using amastatin and properties of aminopeptidase A from pig kidney. | Tobe, H., et al. 1980. Biochim Biophys Acta. 613: 459-68. PMID: 7448199
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Glutamic acid beta-naphthylamide, 1 g | sc-295281 | 1 g | $128.00 | |||
L-Glutamic acid beta-naphthylamide, 5 g | sc-295281A | 5 g | $850.00 |