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L-Fucitol (CAS 13074-06-1)

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Alternate Names:
6-Deoxy-L-galactitol
Application:
L-Fucitol is A substrate of L-fucitol isomerase
CAS Number:
13074-06-1
Purity:
≥98%
Molecular Weight:
166.17
Molecular Formula:
C6H14O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Fucitol is a carbohydrate found in some plant species. It is also a substrate of L-fucose isomerase which catalyzes the aldose–ketose isomerization of L-fucitol. It can be used as a biochemical marker for identifying and quantifying the presence of certain compounds in biological samples. L-Fucitol may act to inhibit the activity of certain enzymes, such as phospholipase A2 and cyclooxygenase-2, as well as modulate the activity of certain hormones, such as glucagon and insulin. In vitro, L-Fucitol can be used to study the effects of various compounds on cell proliferation, differentiation, apoptosis, gene expression, and metabolic pathways.


L-Fucitol (CAS 13074-06-1) References

  1. Water-soluble constituents of caraway: aromatic compound, aromatic compound glucoside and glucides.  |  Matsumura, T., et al. 2002. Phytochemistry. 61: 455-9. PMID: 12377243
  2. X-ray structures of Bacillus pallidus d-arabinose isomerase and its complex with l-fucitol.  |  Takeda, K., et al. 2010. Biochim Biophys Acta. 1804: 1359-68. PMID: 20123133
  3. L-Xylo-3-hexulose, a new rare sugar produced by the action of acetic acid bacteria on galactitol, an exception to Bertrand Hudson's rule.  |  Xu, Y., et al. 2021. Biochim Biophys Acta Gen Subj. 1865: 129740. PMID: 32956752
  4. Studies on a microchemical method for the determination of the degree of polymerization of neutral oligo- and polysaccharides. I. Quantitative separation of trace amounts of alditols from mixtures with a large excess of monosaccharides.  |  Yamaguchi, H., et al. 1976. J Biochem. 79: 299-303. PMID: 5428
  5. Biosynthesis and catabolism of 6-deoxy L-talitol by Klebsiella aerogenes mutants.  |  St Martin, EJ. and Mortlock, RP. 1980. J Bacteriol. 141: 1157-62. PMID: 6988406
  6. Structure and mechanism of L-fucose isomerase from Escherichia coli.  |  Seemann, JE. and Schulz, GE. 1997. J Mol Biol. 273: 256-68. PMID: 9367760
  7. Further experiments on the oxidation of sugar acetals and thioacetals by Acetobacter suboxydans  |  Williams, D. T., & Jones, J. K. N. 1967. Canadian Journal of Chemistry. 45(7): 741-744.
  8. Monobutylidene acetals of 1-deoxy-D-galactitol  |  Bonner, T. G., Bourne, E. J., Lewis, D., & Yüceer, L. 1975. Journal of the Chemical Society, Perkin Transactions 1. (14): 1323-1325.
  9. Introduction of a new selective oxidation procedure into carbohydrate chemistry-An efficient conversion of D-galactose into L-fucose  |  Kristen, H., Wrubel, V. F., Mahrwald, R., & Schick, H. 1988. Journal of Carbohydrate Chemistry. 7(1): 277-281.
  10. Carbohydrates as chemical constituents of biowaste composts and their humic and fulvic acids  |  Hänninen, K. I., Kovalainen, J. T., & Korvola, J. 1995. Compost Science & Utilization. 3(4): 51-68.
  11. Anticancer property of Selaginella bryopteris (L.) Bak. against hepatocellular carcinoma in vitro and in vivo  |  Pal, L. C., Gautam, A., Pande, V., & Rao, C. V. 2022. Phytomedicine Plus. 2(1): 100201.
  12. Wound Healing Activity of the Flavonoid-Enriched Fraction of Selaginella bryopteris Linn. against Streptozocin-Induced Diabetes in Rats  |  Gautam, A., Kumar, V., Azmi, L., Rao, C. V., Khan, M. M., Mukhtar, B.,.. & Alam, A. 2023. Separations. 10(3): 166.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Fucitol, 250 mg

sc-215214
250 mg
$98.00