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L-Dehydro Ascorbic Acid (CAS 490-83-5)

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Application:
L-Dehydro Ascorbic Acid is the reversibly oxidized form of ascorbic acid
CAS Number:
490-83-5
Purity:
≥97%
Molecular Weight:
174.11
Molecular Formula:
C6H6O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Dehydro Ascorbic Acid (DHA) is an oxidized form of ascorbic acid (vitamin C) and possesses potent antioxidant properties. Extensive research conducted in the past decade has shed light on its biomedical applications. Investigations have primarily focused on its potential effects on various diseases, including cancer, diabetes, and Alzheimer′s disease. Moreover, studies have explored the impact of L-Dehydro Ascorbic Acid on the immune system and its ability to counteract oxidative stress. Research efforts have delved into comprehending how L-Dehydro Ascorbic Acid influences cell proliferation, apoptosis, gene expression, as well as protein and enzyme activity. Although the exact mechanism of action of L-Dehydro Ascorbic Acid remains incompletely understood, it is believed to function as an antioxidant by scavenging reactive oxygen species and safeguarding cells against oxidative damage. Interestingly, L-Dehydro Ascorbic Acid may also exhibit pro-oxidant properties, which can induce cell death.


L-Dehydro Ascorbic Acid (CAS 490-83-5) References

  1. Evaluation of gaseous chlorine dioxide as a sanitizer for killing Salmonella, Escherichia coli O157:H7, Listeria monocytogenes, and yeasts and molds on fresh and fresh-cut produce.  |  Sy, KV., et al. 2005. J Food Prot. 68: 1176-87. PMID: 15954704
  2. Alteration of chemical behavior of L-ascorbic acid in combination with nickel sulfate at different pH solutions in vitro.  |  Maniyar, SA., et al. 2012. Asian Pac J Trop Biomed. 2: 220-2. PMID: 23569901
  3. Modification of carbon paste electrode with Fe(III)-clinoptilolite nano-particles for simultaneous voltammetric determination of acetaminophen and ascorbic acid.  |  Sharifian, S. and Nezamzadeh-Ejhieh, A. 2016. Mater Sci Eng C Mater Biol Appl. 58: 510-20. PMID: 26478339
  4. Inorganic pyrophosphatase in mineralizing hamster molars. IV. Modification of the inhibition of EDTA, diphosphonates and L-ascorbic acid by Zn2+ and C02+.  |  Wöltgens, JH. 1974. Calcif Tissue Res. 16: 201-7. PMID: 4217214
  5. Antiscorbutic activity of D-araboascorbic acid.  |  Fabianek, J. and Herp, A. 1967. Proc Soc Exp Biol Med. 125: 462-5. PMID: 6028565
  6. Quantitative reversed phase HPLC analysis of L-ascorbic acid (Vitamin C) and identification of its degradation products  |  , et al., (1987). Chromatographia. volume 24: pages 371–376.
  7. PYRAZINES IN THE REACTION OF L-DEHYDROASCORBIC ACID WITH AMMONIA AND GLYCINE  |   and J. DAVÍDEK, J. VELÍŠEK, Z. ZELINKOVÁ, V. KUBELKA. January 1977. Journal of Food Science. Volume42, Issue1: Pages 277-278.
  8. Dehydroascorbic acid levels in fresh fruit and vegetables in relation to total vitamin C activity  |  . 1984,. J. Agric. Food Chem. 32, 4:, 836–838.
  9. Oxidation of L-ascorbic acid by trisoxalatoferrate(III) in aqueous solution. Kinetic and spectroscopic evidence for the formation of an intermediate species  |  P Martinez, J Zuluaga, D Uribe, R Van Eldik. April 1987,. Inorganica Chimica Acta. Volume 136, Issue 1,: Pages 11-16.
  10. Kinetics of Ascorbic Acid Degradation and Non-Enzymic Browning in Potatoes  |  WAM McMinn, TRA Magee -. December 1997,. Food and Bioproducts Processing. Volume 75, Issue 4,: Pages 223-231.
  11. Molecularly imprinted polyaniline-ferrocene-sulfonic acid-Carbon dots modified pencil graphite electrodes for chiral selective sensing of D-Ascorbic acid and L-Ascorbic acid: A clinical biomarker for preeclampsia  |  I Pandey, SS Jha - Electrochimica acta, 2015 - Elsevier. 2015. Electrochimica Acta. Volume 182, 10 November 2015,: Pages 917-928.
  12. Electrochemical oxidation and determination of ascorbic acid present in natural fruit juices using a methionine modified carbon paste electrode  |  . 2012,4,. Anal. Methods,. Issue 11,: 3754-3759.
  13. Chiral Intermediates and the Oscillatory Effect of Circular Dichroism in the Belousov – Zhabotinskii Type Reaction of L-Ascorbic Acid  |   and Thomas Buhse and Wolfram Thiemann. June 2, 2014. Zeitschrift für Naturforschung B. Volume 46 Issue 10.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Dehydro Ascorbic Acid, 500 mg

sc-218636
500 mg
$155.00