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L-Aspartic acid dimethyl ester hydrochloride (CAS 32213-95-9)

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Alternate Names:
Dimethyl L-aspartate hydrochloride; L-Asp(OMe)-Ome.HCl
CAS Number:
32213-95-9
Molecular Weight:
197.62
Molecular Formula:
C6H12ClNO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Aspartic acid dimethyl ester hydrochloride is as an inhibitor for serine proteases, enzymes responsible for protein degradation. By creating a covalent bond with the serine residue within the enzyme′s active site, L-Aspartic acid dimethyl ester hydrochloride inhibits its activity. Dimethyl L-Aspartate Hydrochloride has been utilized in crafting enzyme and pH dual-reactive L-amino acid-based biodegradable polymer nanocarriers.


L-Aspartic acid dimethyl ester hydrochloride (CAS 32213-95-9) References

  1. Self-organization of a polymerizable bolaamphiphile bearing a diacetylene group and L-aspartic acid group.  |  Yin, S., et al. 2009. Langmuir. 25: 8968-73. PMID: 19334690
  2. Conformationally constrained peptides. Chirospecific synthesis of 4-alkyl-substituted. gamma.-lactam-bridged dipeptides from L-aspartic acid  |  Jean Pierre Wolf and Henry Rapoport. 1989. J. Org. Chem. 54: 3164–3173.
  3. Polymerizable dendrimers: 2. Mono‐methacryl modified dendrimers containing up to 16 ester functions via stepwise condensations of L‐aspartic acids  |  M. Niggemann, H. Ritter. 1996. Acta Polymerica. 47: 351-356.
  4. Polymerizable ring-shaped molecules containing aspartic acid: synthesis and free radical polymerization of a macrocycle derived from (N'-methacryloyl-11-aminoundecanoyl)-α,β-bis(4,9-dioxa-dodecane-1,12-diamine)-L-aspartic acid amide by addition to toluene-2,4-diisocyanate  |  Matthias Niggemann & Helmut Ritter. 1999. Designed Monomers and Polymers. 2: 19-28.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Aspartic acid dimethyl ester hydrochloride, 5 g

sc-235468
5 g
$64.00