Date published: 2025-12-18

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L-Ascorbyl 2,6-Dibutyrate (CAS 4337-04-6)

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Alternate Names:
2,6-Di-O-butyryl-L-ascorbic Acid
CAS Number:
4337-04-6
Molecular Weight:
316.30
Molecular Formula:
C14H20O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Ascorbyl 2,6-dibutyrate, a derivative of vitamin C, has been extensively studied in scientific research for its antioxidant properties and potential applications in various fields. Studies have investigated its mechanism of action, revealing its ability to scavenge free radicals and protect cells from oxidative stress-induced damage. This compound has been utilized in research exploring its role in skin biology, particularly in the context of photoprotection and anti-aging effects. L-Ascorbyl 2,6-dibutyrate has been shown to enhance collagen synthesis and inhibit the formation of reactive oxygen species (ROS) induced by UV radiation, suggesting its potential as a photoprotective agent in skincare formulations. Additionally, research has focused on its use in food preservation, where it acts as an antioxidant to prevent lipid oxidation and extend the shelf life of food products. Furthermore, L-Ascorbyl 2,6-dibutyrate has been investigated for its potential as a drug delivery vehicle, exploiting its ability to undergo hydrolysis in vivo to release active vitamin C. By elucidating the mechanisms of action and exploring its diverse applications, researchers aim to further understand the potential benefits of L-Ascorbyl 2,6-dibutyrate in various scientific disciplines, including skincare, food science, and pharmaceuticals.


L-Ascorbyl 2,6-Dibutyrate (CAS 4337-04-6) References

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  2. A quantitative approach to the free radical interaction between alpha-tocopherol and the coantioxidants eugenol, resveratrol or ascorbate.  |  Kadoma, Y., et al. 2006. In Vivo. 20: 61-7. PMID: 16433030
  3. A quantitative approach to the free radical interaction between alpha-tocopherol or ascorbate and flavonoids.  |  Fujisawa, S., et al. 2006. In Vivo. 20: 445-52. PMID: 16900773
  4. Free radical interaction between vitamin E (alpha-, beta-, gamma- and delta-tocopherol), ascorbate and flavonoids.  |  Kadoma, Y., et al. 2006. In Vivo. 20: 823-7. PMID: 17203774
  5. Countercurrent Chromatographic Separation of Lipophilic Ascorbic Acid Derivatives and Extract from Kadsura Coccinea Using Hydrophobic Organic-Aqueous Two-Phase Solvent Systems.  |  Shinomiya, K., et al. 2009. J Liq Chromatogr Relat Technol. 32: 2361-2371. PMID: 20046934
  6. Radical-scavenging activity of melatonin, either alone or in combination with vitamin E, ascorbate or 2-mercaptoethanol as co-antioxidants, using the induction period method.  |  Kadoma, Y. and Fujisawa, S. 2011. In Vivo. 25: 49-53. PMID: 21282734
  7. Dietary antioxidant synergy in chemical and biological systems.  |  Wang, S. and Zhu, F. 2017. Crit Rev Food Sci Nutr. 57: 2343-2357. PMID: 26176981
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Ascorbyl 2,6-Dibutyrate, 1 g

sc-295261
1 g
$255.00