Date published: 2025-12-20

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L-α-Phosphatidyl-D-myo-inositol 3,4-diphosphate, dioctanoyl

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Molecular Weight:
746.57
Molecular Formula:
C25H49O19P3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-α-Phosphatidyl-D-myo-inositol 3,4-diphosphate, dioctanoyl is a synthetic phospholipid characterized by its unique structural components, featuring a glycerol backbone esterified with two octanoic acid chains and a myo-inositol head group phosphorylated at the 3rd and 4th positions. This configuration imbues the molecule with specific physical and chemical properties that make it particularly suitable for detailed research in non-medical fields. The relatively short octanoic acid chains confer increased solubility and distinct membrane-forming capabilities, allowing for the study of lipid bilayers and micellar systems. The dual phosphate groups on the inositol ring introduce a high negative charge density, crucial for investigating the electrostatic interactions within lipid assemblies and their impact on membrane structure and dynamics. This phospholipid is extensively used in biophysical studies to model and understand the behavior of phosphoinositide-rich membranes, which are fundamental in cellular processes such as signaling and membrane trafficking in a purely research context. Such studies contribute significantly to the fields of materials science and nanotechnology, particularly in the development of lipid-based delivery systems and the fabrication of biomimetic membranes, providing foundational insights that drive innovation in non-biological applications.


L-α-Phosphatidyl-D-myo-inositol 3,4-diphosphate, dioctanoyl References

  1. Distinct phosphatidylinositol 3-kinase lipid products accumulate upon oxidative and osmotic stress and lead to different cellular responses.  |  Van der Kaay, J., et al. 1999. J Biol Chem. 274: 35963-8. PMID: 10585485
  2. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate.  |  Franke, TF., et al. 1997. Science. 275: 665-8. PMID: 9005852

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-α-Phosphatidyl-D-myo-inositol 3,4-diphosphate, dioctanoyl, 100 µg

sc-300869
100 µg
$535.00