L-Alanyl-L-proline (CAS 13485-59-1)

L-Alanyl-L-proline is an alanyl dipeptide. This specific arrangement places L-alanine at the N-terminal and L-proline at the C-terminal. Both amino acids are in their L-configuration, which is the naturally occurring and biologically active form for most amino acids in proteins. The presence of proline, a cyclic amino acid, next to any other amino acid, including alanine, can have interesting implications for the secondary structure of peptides and proteins. Proline is known to introduce a kink or turn in the polypeptide chain due to its rigid cyclic structure, which restricts the rotation around the N-Cα bond. This property makes dipeptides like L-Alanyl-L-proline interesting subjects of study in understanding protein folding, structure, and dynamics. In biochemical and biophysical research, dipeptides like L-Alanyl-L-proline are often used to study the fundamental principles of peptide behavior, such as solubility, stability, and interactions with other molecules. These small peptides can serve as model systems to explore the roles of specific amino acid residues in larger proteins, including how they influence protein structure, function, and interaction with other biomolecules.