Molecular structure of L-Alanyl-L-alanyl-L-phenylalanine 7-amido-4-methylcoumarin, CAS Number: 62037-41-6
L-Alanyl-L-alanyl-L-phenylalanine 7-amido-4-methylcoumarin (CAS 62037-41-6)
Alternate Names:
Ala-Ala-Phe-7-amido-4-methylcoumarin
Application:
L-Alanyl-L-alanyl-L-phenylalanine 7-amido-4-methylcoumarin is a peptide substrate for chymotrypsin and tripeptidyl peptidase II
CAS Number:
62037-41-6
Purity:
≥98%
Molecular Weight:
464.51
Molecular Formula:
C25H28N4O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
L-Alanyl-L-alanyl-L-phenylalanine 7-amido-4-methylcoumarin is a substrate used in enzymatic assays to measure the activity of peptidases and proteases. When introduced to the experimental system, L-Alanyl-L-alanyl-L-phenylalanine 7-amido-4-methylcoumarin is cleaved by the target enzyme, resulting in the release of 7-amido-4-methylcoumarin. This fluorescent compound emits a detectable signal upon excitation, allowing for the quantification of enzyme activity. The mechanism of action involves the specific recognition and cleavage of the peptide bond by the enzyme, leading to the generation of the fluorescent product. Its use provides insights into the mechanisms and regulation of proteolytic pathways.
L-Alanyl-L-alanyl-L-phenylalanine 7-amido-4-methylcoumarin (CAS 62037-41-6) References
- Cln3 function is linked to osmoregulation in a Dictyostelium model of Batten disease. | Mathavarajah, S., et al. 2018. Biochim Biophys Acta Mol Basis Dis. 1864: 3559-3573. PMID: 30251676
- Comparative transcriptomics reveals mechanisms underlying cln3-deficiency phenotypes in Dictyostelium. | Huber, RJ. and Mathavarajah, S. 2019. Cell Signal. 58: 79-90. PMID: 30771446
Substrate of:
Chymotrypsin, and TPPII.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Alanyl-L-alanyl-L-phenylalanine 7-amido-4-methylcoumarin, 25 mg | sc-218626 | 25 mg | $168.00 |