Date published: 2026-4-5

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L-Alanine methyl ester hydrochloride (CAS 2491-20-5)

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Alternate Names:
H-Ala-OMe.HCl
CAS Number:
2491-20-5
Purity:
≥99%
Molecular Weight:
139.58
Molecular Formula:
C4H9NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Alanine methyl ester hydrochloride (L-AMEH) is a versatile white crystalline powder extensively utilized in the synthesis of pharmaceuticals, cosmetics, and various other products. It belongs to the amino acid family and is derived from alanine, an essential amino acid found in proteins. Besides its role in synthetic processes, L-Alanine methyl ester hydrochlorid has attracted attention in scientific research due to its potential physiological and biochemical effects. L-Alanine methyl ester hydrochlorid has found numerous applications in scientific research. Researchers have used it as a reagent for peptide and molecule synthesis, as a substrate to study enzymes, and as a ligand to investigate protein-ligand interactions. Moreover, it has been instrumental in studying cell signaling pathways and gene expression regulation. While the complete mechanism of action of L-Alanine methyl ester hydrochlorid remains elusive, it is understood that the compound interacts with various proteins and enzymes. Some researchers have posited that L-Alanine methyl ester hydrochlorid might function as an allosteric modulator, impacting enzyme activity in intriguing ways.


L-Alanine methyl ester hydrochloride (CAS 2491-20-5) References

  1. Nalidixic acid prodrugs: amides from amino acid ester and nalidixic acid.  |  Taori, A., et al. 1991. Arch Pharm Res. 14: 48-51. PMID: 10319121
  2. Development of a prodrug of salicylic acid, salicylic acid-L-alanine conjugate, utilizing hydrolysis by rabbit intestinal microorganisms.  |  Nakamura, J., et al. 1992. J Pharm Pharmacol. 44: 295-9. PMID: 1355539
  3. In situ-forming pharmaceutical organogels based on the self-assembly of L-alanine derivatives.  |  Couffin-Hoarau, AC., et al. 2004. Pharm Res. 21: 454-7. PMID: 15070096
  4. Characterization and biocompatibility of organogels based on L-alanine for parenteral drug delivery implants.  |  Motulsky, A., et al. 2005. Biomaterials. 26: 6242-53. PMID: 15916802
  5. Synthesis, separation and anti-HIV activity of distereoisomers of N-[p-(4-bromophenyl) -2',3'-didehydro-3'-deoxy-5'-thymidylyl]-L-alanine methyl ester (stampidine).  |  Venkatachalam, TK., et al. 2006. Arzneimittelforschung. 56: 152-8. PMID: 16570823
  6. Synthesis of some new pyridine-2,6-carboxamide-derived Schiff bases as potential antimicrobial agents.  |  Al-Omar, MA. and Amr, Ael-G. 2010. Molecules. 15: 4711-21. PMID: 20657387
  7. Enzymatic production of L-alanyl-L-glutamine by recombinant E. coli expressing α-amino acid ester acyltransferase from Sphingobacterium siyangensis.  |  Hirao, Y., et al. 2013. Biosci Biotechnol Biochem. 77: 618-23. PMID: 23470770
  8. N-acylated alanine methyl esters (NAMEs) from Roseovarius tolerans, structural analogs of quorum-sensing autoinducers, N-acylhomoserine lactones.  |  Bruns, H., et al. 2013. Chem Biodivers. 10: 1559-73. PMID: 24078590
  9. Poly(amino acid)-based thermoresponsive molecularly imprinted magnetic nanoparticles for specific recognition and release of lysozyme.  |  Ji, S., et al. 2016. Anal Chim Acta. 909: 60-6. PMID: 26851085
  10. Preparation and evaluation of a chiral HPLC stationary phase based on cone calix[4]arene functionalized at the upper rim with l-alanine units.  |  Yaghoubnejad, S., et al. 2018. Biomed Chromatogr. 32: PMID: 29059471
  11. Oxygenated N-Acyl Alanine Methyl Esters (NAMEs) from the Marine Bacterium Roseovarius tolerans EL-164.  |  Bruns, H., et al. 2018. J Nat Prod. 81: 131-139. PMID: 29261310
  12. Water-soluble photoluminescent d-mannose and l-alanine functionalized silicon nanocrystals and their application to cancer cell imaging.  |  Zhai, Y., et al. 2014. J Mater Chem B. 2: 8427-8433. PMID: 32262014
  13. Synthesis and Biological Properties of Alanine-Grafted Hydroxyapatite Nanoparticles.  |  Dorm, BC., et al. 2022. Life (Basel). 13: PMID: 36676065
  14. Conformation of small peptides. II. Synthesis and infrared studies of small peptides.  |  Shields, JE., et al. 1968. J Am Chem Soc. 90: 3549-56. PMID: 5651563
  15. Synthesis of polypeptides with known repeating sequence of amino acids.  |  Kovacs, J. and Kapoor, A. 1965. J Am Chem Soc. 87: 118-9. PMID: 5826970

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Alanine methyl ester hydrochloride, 5 g

sc-250212
5 g
$23.00

L-Alanine methyl ester hydrochloride, 25 g

sc-250212A
25 g
$91.00