Molecular structure of L-Alanine, CAS Number: 56-41-7
L-Alanine (CAS 56-41-7)
Alternate Names:
(S)-2-Aminopropionic acid; H-Ala-OH
Application:
L-Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle
CAS Number:
56-41-7
Molecular Weight:
89.09
Molecular Formula:
C3H7NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
L-Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle between muscle tissue and the liver. In amino acid-degrading tissues such as muscle, amino groups are pooled as glutamate by transamination reactions. The amino group of glutamate is transferred to pyruvate via alanine aminotransferase, forming alanine and alpha-ketoglutarate. The alanine is passed into the blood and transported to the liver. This reaction is reversed in the liver where pyruvate can be used in gluconeogenesis to form glucose, which may return to other tissues through the circulatory system.
L-Alanine (CAS 56-41-7) References
- Efficient L-Alanine Production by a Thermo-Regulated Switch in Escherichia coli. | Zhou, L., et al. 2016. Appl Biochem Biotechnol. 178: 324-37. PMID: 26453031
- Diminished brush border membrane Na-dependent L-alanine transport in acute viral enteritis in piglets. | Rhoads, JM., et al. 1989. J Pediatr Gastroenterol Nutr. 9: 225-31. PMID: 2681649
- Alanine dehydrogenase and its applications - A review. | Dave, UC. and Kadeppagari, RK. 2019. Crit Rev Biotechnol. 39: 648-664. PMID: 31018703
- L-Alanine Exporter, AlaE, of Escherichia coli Functions as a Safety Valve to Enhance Survival under Feast Conditions. | Katsube, S., et al. 2019. Int J Mol Sci. 20: PMID: 31591285
- L-Alanine specifically potentiates fluoroquinolone efficacy against Mycobacterium persisters via increased intracellular reactive oxygen species. | Zhen, J., et al. 2020. Appl Microbiol Biotechnol. 104: 2137-2147. PMID: 31940082
- Na+-NQR Confers Aminoglycoside Resistance via the Regulation of l-Alanine Metabolism. | Jiang, M., et al. 2020. mBio. 11: PMID: 33203750
- L-alanine supplementation improves blood glucose level and biochemical indices in alloxan-induced diabetic rats. | Dandare, SU., et al. 2021. J Food Biochem. 45: e13590. PMID: 33346923
- L-Alanine Prototrophic Suppressors Emerge from L-Alanine Auxotroph through Stress-Induced Mutagenesis in Escherichia coli. | Mishima, H., et al. 2021. Microorganisms. 9: PMID: 33668720
- Metabolic engineering of microorganisms for L-alanine production. | Liu, P., et al. 2022. J Ind Microbiol Biotechnol. 49: PMID: 34410417
- Exogenous d-β-hydroxybutyrate lowers blood glucose in part by decreasing the availability of L-alanine for gluconeogenesis. | Soto-Mota, A., et al. 2022. Endocrinol Diabetes Metab. 5: e00300. PMID: 34787952
- Stable Isotope-Labeled Precursor Tracing Reveals that l-Alanine is Converted to l-Theanine via l-Glutamate not Ethylamine in Tea Plants In Vivo. | Fu, X., et al. 2021. J Agric Food Chem. 69: 15354-15361. PMID: 34904439
- Nutrient L-Alanine-Induced Germination of Bacillus Improves Proliferation of Spores and Exerts Probiotic Effects in vitro and in vivo. | Lu, S., et al. 2021. Front Microbiol. 12: 796158. PMID: 34925306
- Biomedical applications of L-alanine produced by Pediococcus acidilactici BD16 (alaD+). | Sharma, A., et al. 2022. Appl Microbiol Biotechnol. 106: 1435-1446. PMID: 35089399
Inhibitor of:
ASCT1, GPx-8, PKLR, and SLC7A6.Activator of:
AGT1, AGXT2, AlaRS, Aminopeptidase P1, GAP1-InsP4 BP, GLOD5, GLUD1, GOT1L1, GPT2, GRHPR, L-serine dehydratase, liver FBPase, NAALADL1, PAT2, secretin, SLC6A14, SNAT1, and SNAT3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Alanine, 1 g | sc-396825 | 1 g | $31.00 | |||
L-Alanine, 100 g | sc-396825A | 100 g | $100.00 | |||
L-Alanine, 500 g | sc-396825B | 500 g | $430.00 | |||
L-Alanine, 1 kg | sc-396825C | 1 kg | $740.00 |