Molecular structure of L-750,667 trihydrochloride, CAS Number: 1021868-80-3
L-750,667 trihydrochloride (CAS 1021868-80-3)
Alternate Names:
3-[4-(4-Iodophenyl)piperazin-1-yl]methyl-1H-pyrrolo[2,3-b]pyridine trihydrochloride
CAS Number:
1021868-80-3
Molecular Weight:
527.66
Molecular Formula:
C18H19IN4•3HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
This product is a selective D4 dopamine receptor antagonist.
L-750,667 trihydrochloride (CAS 1021868-80-3) References
- Dopamine D4 receptor antagonist inhibits melanogenesis through transcriptional downregulation of MITF via ERK signalling. | Jung, JM., et al. 2016. Exp Dermatol. 25: 325-8. PMID: 26782007
- Downregulation of melanogenesis: drug discovery and therapeutic options. | Pillaiyar, T., et al. 2017. Drug Discov Today. 22: 282-298. PMID: 27693716
- Recent development of signaling pathways inhibitors of melanogenesis. | Pillaiyar, T., et al. 2017. Cell Signal. 40: 99-115. PMID: 28911859
- 3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor. | Kulagowski, JJ., et al. 1996. J Med Chem. 39: 1941-2. PMID: 8642550
- Identification and pharmacological characterization of [125I]L-750,667, a novel radioligand for the dopamine D4 receptor. | Patel, S., et al. 1996. Mol Pharmacol. 50: 1658-64. PMID: 8967990
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-750,667 trihydrochloride, 5 mg | sc-300865 | 5 mg | $284.00 |