Molecular structure of L-4-Fluoro-phenyl-alanine, CAS Number: 1132-68-9
L-4-Fluoro-phenyl-alanine (CAS 1132-68-9)
Application:
L-4-Fluoro-phenyl-alanine is a TH substrate which appears to inhibit mitosis and arrest cells in G2
CAS Number:
1132-68-9
Purity:
≥99%
Molecular Weight:
183.182
Molecular Formula:
C9H10FNO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
L-4-Fluoro-phenyl-alanine is a derivative of the essential amino acid phenylalanine. This synthetic compound closely resembles naturally occurring L-Phenylalanine (L-Phe), differing only in the substitution of a hydrogen atom with a fluorine atom. The unique properties of L-4-Fluoro-phenyl-alanine have prompted its exploration in vitro studies. In vitro studies, on the other hand, have focused on utilizing L-4-Fluoro-phenyl-alanine as a substrate for enzymes involved in protein synthesis. While the precise mechanism of action of L-4-Fluoro-phenyl-alanine remains incompletely understood, it is believed to enhance the bioavailability of certain drugs and serve as a substrate for specific enzymes involved in protein synthesis and drug metabolism.
L-4-Fluoro-phenyl-alanine (CAS 1132-68-9) References
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- Antiviral Activity of Peptide-Based Assemblies. | Hu, T., et al. 2021. ACS Appl Mater Interfaces. 13: 48469-48477. PMID: 34623127
- Synthesis of 2,6-Dimethyltyrosine-Like Amino Acids through Pinacolinamide-Enabled C-H Dimethylation of 4-Dibenzylamino Phenylalanine. | Illuminati, D., et al. 2022. J Org Chem. 87: 2580-2589. PMID: 35138099
- Overexpression of the A4-rolB gene from the pRiA4 of Rhizobium rhizogenes modulates hormones homeostasis and leads to an increase of flavonoid accumulation and drought tolerance in Arabidopsis thaliana transgenic plants. | Veremeichik, GN., et al. 2022. Planta. 256: 8. PMID: 35690636
- Chromosome condensing ability of mitotic proteins diminished by the substitution of phenylalanine with parafluorophenylalanine. | Sunkara, PS., et al. 1981. Eur J Cell Biol. 23: 312-6. PMID: 7193581
- Regulation of rat liver phenylalanine hydroxylase. I. Kinetic properties of the enzyme's iron and enzyme reduction site. | Shiman, R., et al. 1994. J Biol Chem. 269: 24637-46. PMID: 7929135
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Substrate of:
TH.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-4-Fluoro-phenyl-alanine, 100 mg | sc-207785 | 100 mg | $48.00 | |||
L-4-Fluoro-phenyl-alanine, 1 g | sc-207785A | 1 g | $176.00 |