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L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride (CAS 1421-65-4)

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Alternate Names:
Methyl L-DOPA hydrochloride
Application:
L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride is a precursor to L-DOPA that crosses blood-brain barrier
CAS Number:
1421-65-4
Purity:
≥98%
Molecular Weight:
247.68
Molecular Formula:
C10H13NO4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride is a compound utilized in various research disciplines, including chemistry and neurobiology. It is a methyl ester derivative of L-DOPA, which is an important compound in the study of dopamine biosynthesis and metabolism. In organic synthesis, L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride is used as a starting material or intermediate for the preparation of more complex molecules that may have biological relevance or for the modification of peptides and proteins. Chemists value this compound for its protected catechol structure, which allows selective reactions to be carried out at other sites of the molecule. In neurobiological research, it is used as a tool to understand the dopaminergic system and the enzymatic pathways involved in catecholamine production. Additionally, this compound is employed in the development of analytical methods for detecting and quantifying catecholamine precursors and their derivatives. The hydrochloride salt form improves its solubility in water, which is beneficial for various biochemical assays.


L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride (CAS 1421-65-4) References

  1. The effects on central dopamine function of chronic L-dopa (methyl ester hydrochloride) treatment of mice.  |  Tabar, J., et al. 1989. Pharmacol Biochem Behav. 33: 139-46. PMID: 2789405
  2. Intranasal administration of the dopaminergic agonists L-DOPA, amphetamine, and cocaine increases dopamine activity in the neostriatum: a microdialysis study in the rat.  |  De Souza Silva, MA., et al. 1997. J Neurochem. 68: 233-9. PMID: 8978730

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride, 500 mg

sc-250211
500 mg
$173.00

L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride, 1 g

sc-250211A
1 g
$204.00