Molecular structure of L-2,4-Diaminobutyric Acid, Dihydrochloride, CAS Number: 1883-09-6
L-2,4-Diaminobutyric Acid, Dihydrochloride (CAS 1883-09-6)
Alternate Names:
(2S)-2,4-Diamino-butanoic Acid Dihydrochloride
Application:
L-2,4-Diaminobutyric Acid, Dihydrochloride is an antitumor inhibitor of GABA transaminase
CAS Number:
1883-09-6
Molecular Weight:
191.06
Molecular Formula:
C4H10N2O2•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A pharmacological tool and potential chiral building block. Found to inhibit GABA transaminase, thus producing an elevation of GABA level, and to have an antitumor activity. It is also used as an internal standard for amino acid analysis.
L-2,4-Diaminobutyric Acid, Dihydrochloride (CAS 1883-09-6) References
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- Distinguishing the cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) from other diamino acids. | Banack, SA., et al. 2011. Toxicon. 57: 730-8. PMID: 21329717
- Selective LC-MS/MS method for the identification of BMAA from its isomers in biological samples. | Jiang, L., et al. 2012. Anal Bioanal Chem. 403: 1719-30. PMID: 22526645
- Detection of cyanobacterial neurotoxin β-N-methylamino-l-alanine within shellfish in the diet of an ALS patient in Florida. | Banack, SA., et al. 2014. Toxicon. 90: 167-73. PMID: 25123936
- Autoradiographic localization of [3H] gamma-aminobutyric acid in neuronal elements of the rat gastric antrum and intestine. | Krantis, A. and Webb, T. 1989. J Auton Nerv Syst. 29: 41-8. PMID: 2534397
- Highly sensitive quantification for human plasma-targeted metabolomics using an amine derivatization reagent. | Arashida, N., et al. 2017. Anal Chim Acta. 954: 77-87. PMID: 28081817
- Identification of O-acetylhomoserine sulfhydrylase, a putative enzyme responsible for methionine biosynthesis in Clostridioides difficile: Gene cloning and biochemical characterizations. | Kulikova, VV., et al. 2019. IUBMB Life. 71: 1815-1823. PMID: 31359602
- Application of N-methyl-D-aspartate receptor nanopore in screening ligand molecules. | Li, SP., et al. 2020. Bioelectrochemistry. 134: 107534. PMID: 32335354
- The Changes in Cyanobacterial Concentration of β-Methylamino-L-Alanine during a Bloom Event. | Peters, SJ., et al. 2022. Molecules. 27: PMID: 36364208
- Simultaneous Analysis of Cyanotoxins β-N-methylamino-L-alanine (BMAA) and Microcystins-RR, -LR, and -YR Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). | Pravadali-Cekic, S., et al. 2023. Molecules. 28: PMID: 37764509
- Antitumor activity of L-2,4 diaminobuturic acid against mouse fibrosarcoma cells in vitro and in vivo. | Ronquist, G., et al. 1980. J Cancer Res Clin Oncol. 96: 259-68. PMID: 7430241
- Internal standards for amino acid analysis. | Riordan, JF. and Giese, RW. 1977. Methods Enzymol. 47: 31-40. PMID: 927189
- On the specificity of the uridine diphospho-N-acetylmuramyl-alanyl-D-glutamic acid: diamino acid ligase of Bifidobacterium globosum. | Hammes, WP., et al. 1977. Arch Microbiol. 115: 95-102. PMID: 931511
Inhibitor of:
ABAT, and CNDP2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-2,4-Diaminobutyric Acid, Dihydrochloride, 1 g | sc-218625 | 1 g | $106.00 |