Molecular structure of L-1-Tosylamide-2-phenylethylchloromethyl Ketone, CAS Number: 329-30-6
L-1-Tosylamide-2-phenylethylchloromethyl Ketone (CAS 329-30-6)
Alternate Names:
T.P.C.K.
Application:
L-1-Tosylamide-2-phenylethylchloromethyl Ketone is a protease inhibitor
CAS Number:
329-30-6
Molecular Weight:
351.8
Molecular Formula:
C17H18ClNO3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
This product inhibits protease, and inactivates chymotrypsin but does not inactivate trypsin. It has been shown to irreversibly inhibit chymotrypsin-like serine proteases including ficin, bromelain, and papain. It has also been shown to inhibits I kappaB alpha-protease. Inhibition of I kappaB alpha-protease blocks the LPS- or cytokine-induced activation of nuclear factor kappaB (NF-kappaB), which then blocks iNOS induction and COX-2 transcription. It is reported to block apoptosis cell lines through the inhibition of the processing of caspases in some cell lines and to some stimuli. It can also be used in histone isolation.
Inhibitor of:
Protease.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-1-Tosylamide-2-phenylethylchloromethyl Ketone, 100 mg | sc-295238 | 100 mg | $58.00 |