L-(+)-threo-Chloramphenicol (CAS 134-90-7)
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L-(+)-threo-Chloramphenicol is a compound that is studied in various research disciplines, particularly in biochemical assays and enzymology. It serves as a useful tool for investigating the mechanism of action of chloramphenicol acetyltransferase, an enzyme that confers resistance to the bacteriostatic activity of chloramphenicol in certain bacteria. The L-(+)-threo isomer is important for understanding the stereochemical preferences and substrate specificity of this enzyme. Additionally, this compound can be used in the study of protein synthesis in prokaryotic organisms, as it can bind to the bacterial ribosome, allowing researchers to examine the effects of this binding on polypeptide elongation. In the field of biochemistry, L-(+)-threo-Chloramphenicol is also employed as a reference compound in the development of analytical methods for the detection and quantification of chloramphenicol residues in various matrices.
L-(+)-threo-Chloramphenicol (CAS 134-90-7) References
- THE EFFECT OF CHLORAMPHENICOL ON THE GROWTH OF SCENEDESMUS QUADRICAUDA. | TAYLOR, FJ. 1965. J Gen Microbiol. 39: 275-84. PMID: 14324972
- Effect of chloramphenicol and dextramycine on the toxicity of carcinogenic hydrocarbons. | Shabad, LM., et al. 1974. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 82: 13-23. PMID: 4280213
- Effect of D (minus)- and L (plus)-threo-chloramphenicol on nucleotide and related respiratory activities in yeast undergoing metabolic repression and de-repression. | Ball, AJ. and Tustanoff, ER. 1970. Biochim Biophys Acta. 199: 476-89. PMID: 4313887
- Effects of chloramphenicol isomers and erythromycin on enzyme and lipid synthesis induced by oxygen in wild-type and petite yeast. | Gordon, PA., et al. 1972. J Bacteriol. 110: 504-10. PMID: 4336687
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-(+)-threo-Chloramphenicol, 100 mg | sc-391187 | 100 mg | $326.00 |