Molecular structure of KYA1797K, CAS Number: 1956356-56-1
KYA1797K (CAS 1956356-56-1)
Alternate Names:
5Z)-5-[[5-(4-nitrophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid, monopotassium salt
CAS Number:
1956356-56-1
Molecular Weight:
442.5
Molecular Formula:
C17H11N2O6S2•K
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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KYA1797K (CAS 1956356-56-1) References
- Interaction between Wnt/β-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of β-catenin and RAS by targeting the Wnt/β-catenin pathway. | Jeong, WJ., et al. 2018. NPJ Precis Oncol. 2: 5. PMID: 29872723
- A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer. | Park, J., et al. 2019. Sci Rep. 9: 648. PMID: 30679620
- APC loss induces Warburg effect via increased PKM2 transcription in colorectal cancer. | Cha, PH., et al. 2021. Br J Cancer. 124: 634-644. PMID: 33071283
- Lysine demethylase 5B suppresses CC chemokine ligand 14 to promote progression of colorectal cancer through the Wnt/β-catenin pathway. | Yan, G., et al. 2021. Life Sci. 264: 118726. PMID: 33160990
- Suppression of Wnt/β-catenin and RAS/ERK pathways provides a therapeutic strategy for gemcitabine-resistant pancreatic cancer. | Ryu, WJ., et al. 2021. Biochem Biophys Res Commun. 549: 40-46. PMID: 33662667
- Wnt antagonists suppress herpes simplex virus type 1 productive infection. | Harrison, KS. and Jones, C. 2021. Antiviral Res. 191: 105082. PMID: 33961904
- KYA1797K, a Novel Small Molecule Destabilizing β-Catenin, Is Superior to ICG-001 in Protecting against Kidney Aging. | Zhu, M., et al. 2022. Kidney Dis (Basel). 8: 408-423. PMID: 36466073
- A Potential Off-Target Effect of the Wnt/β-Catenin Inhibitor KYA1797K: PD-L1 Binding and Checkpoint Inhibition. | Thuru, X., et al. 2023. Biomed Hub. 8: 1-9. PMID: 36938364
- YAP and β-catenin cooperate to drive H. pylori-induced gastric tumorigenesis. | Li, N., et al. 2023. Gut Microbes. 15: 2192501. PMID: 36959122
- Pentraxin 3 plays a key role in tubular cell senescence and renal fibrosis through inducing β-catenin signaling. | Luo, P., et al. 2023. Biochim Biophys Acta Mol Basis Dis. 1869: 166807. PMID: 37453582
Inhibitor of:
NKD1, and racrac2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KYA1797K, 10 mg | sc-507543 | 10 mg | $215.00 |