Molecular structure of KRIBB3, CAS Number: 129414-88-6
KRIBB3 (CAS 129414-88-6)
See product citations (5)
CAS Number:
129414-88-6
Purity:
≥98%
Molecular Weight:
325.36
Molecular Formula:
C19H19NO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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An inhibitior of PKC-dependent phosphorylation of Hsp27 through its direct binding to Hsp27. Has antimigratory and anti-invasive activities in MDA-MB-231 cells. KRIBB3 blocked phorbol 12-myristate 13-acetate-induced phosphorylation of Hsp27 and tumor cell migration.
KRIBB3 (CAS 129414-88-6) References
Shin K. D. et al., , Blocking tumor cell migration and invasion with biphenyl isoxazole derivative KRIBB3, a synthetic molecule that inhibits Hsp27 phosphorylation. J. Biol. Chem. 280, 41439-41448, (2005)Inhibitor of:
PKC.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KRIBB3, 5 mg | sc-252935 | 5 mg | $322.00 |