Molecular structure of KR-32568, CAS Number: 852146-73-7
KR-32568 (CAS 852146-73-7)
Alternate Names:
[5-(2-Methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine
Application:
KR-32568 is a sodium/H2 exchanger-1 (NHE-1) inhibitor
CAS Number:
852146-73-7
Purity:
≥98%
Molecular Weight:
261.25
Molecular Formula:
C13H12FN3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Sodium/H2 exchanger-1 (NHE-1) inhibitor; inhibited NHE-1-mediated rabbit platelet swelling; in anesthetized rats, reduced infarct size from 67% (control) to 43% (at 0.1 mg/kg) and 24% (at 1.0 mg/kg); reduced number of ventricular premature beats from 530 to 266 (at 0.1 mg/kg) and 115 (at 1.0 mg/kg); reduced ventricular fibrillation incidence from 17 to 8 (0.1 mg/kg) and 0 (1.0 mg/kg); implications for research and treatment of myocardial ischemic diseases.
KR-32568 (CAS 852146-73-7) References
Roh, H.Y., et al., Cardioprotective effects of [5-(2-methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32568) in an anesthetized rat model of ischemia and reperfusion heart injury. Pharmacology 75, 37-44, (2005)Inhibitor of:
NHE, NHE-1, and NHE-6.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KR-32568, 5 mg | sc-252934 | 5 mg | $163.00 |