Date published: 2025-10-2

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KM 11060 (CAS 774549-97-2)

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Alternate Names:
7-Chloro-4-[4-[4-chlorophenyl)sulfonyl]-1-piperazinyl]quinoline
Application:
KM 11060 is it increases the amount functional CFTR at the plasma membrane
CAS Number:
774549-97-2
Molecular Weight:
422.33
Molecular Formula:
C19H17Cl2N3O2S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Inhibits PDE5 activity.


KM 11060 (CAS 774549-97-2) References

Robert et al (2008) Structural analog of Sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect. Mol.Pharmacol. 73 478.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

KM 11060, 10 mg

sc-204029
10 mg
$159.00

KM 11060, 50 mg

sc-204029A
50 mg
$670.00