Molecular structure of Kijanimicin, CAS Number: 78798-08-0
Kijanimicin (CAS 78798-08-0)
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Application:
Kijanimicin is an antibacterial tetronic acid compound
CAS Number:
78798-08-0
Purity:
>99%
Molecular Weight:
1317.5
Molecular Formula:
C67H100NO24
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitro-aminoglycoside. Kijanimicin has potent antibacterial, antimalarial and antitumor activity.
Kijanimicin (CAS 78798-08-0) References
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- Apoptosis and inactivation of the PI3-kinase pathway by tetrocarcin A in breast cancers. | Nakajima, H., et al. 2007. Biochem Biophys Res Commun. 356: 260-5. PMID: 17350598
- Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars. | Zhang, H., et al. 2007. J Am Chem Soc. 129: 14670-83. PMID: 17985890
- Molecular architecture of a C-3'-methyltransferase involved in the biosynthesis of D-tetronitrose. | Bruender, NA., et al. 2010. Biochemistry. 49: 5891-8. PMID: 20527922
- Combined structural and functional investigation of a C-3''-ketoreductase involved in the biosynthesis of dTDP-L-digitoxose. | Kubiak, RL. and Holden, HM. 2011. Biochemistry. 50: 5905-17. PMID: 21598943
- Deglycosylation as a mechanism of inducible antibiotic resistance revealed using a global relational tree for one-component regulators. | Cuthbertson, L., et al. 2013. Chem Biol. 20: 232-40. PMID: 23438752
- Active site architecture of a sugar N-oxygenase. | Thoden, JB., et al. 2013. Biochemistry. 52: 3191-3. PMID: 23621882
- Structural studies on KijD1, a sugar C-3'-methyltransferase. | Dow, GT., et al. 2016. Protein Sci. 25: 2282-2289. PMID: 27595766
- A comprehensive understanding of the biocontrol potential of Bacillus velezensis LM2303 against Fusarium head blight. | Chen, L., et al. 2018. PLoS One. 13: e0198560. PMID: 29856856
- Synthesis of the α-Linked Digitoxose Trisaccharide Fragment of Kijanimicin: An Unexpected Application of Glycosyl Sulfonates. | Mizia, JC., et al. 2022. Org Lett. 24: 731-735. PMID: 35005969
- Special techniques of fast atom bombardment mass spectrometry for the study of oligosaccharide containing macrotetronolide antibiotic, kijanimicin. | Pramanik, BN., et al. 1984. J Antibiot (Tokyo). 37: 818-21. PMID: 6469873
- Antitumor activity of kijanimicin. | Bradner, WT., et al. 1983. J Antibiot (Tokyo). 36: 1078-9. PMID: 6630059
- Kijanimicin (Sch 25663), a novel antibiotic produced by Actinomadura kijaniata SCC 1256. Fermentation, isolation, characterization and biological properties. | Waitz, JA., et al. 1981. J Antibiot (Tokyo). 34: 1101-6. PMID: 7328052
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Kijanimicin, 500 µg | sc-202198 | 500 µg | $356.00 |