Molecular structure of KH7, CAS Number: 330676-02-3
KH7 (CAS 330676-02-3)
Alternate Names:
(E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N′-(5-bromo-2-hydroxybenzylidene)propanehydrazide
Application:
KH7 is a soluble A cyclase inhibitor
CAS Number:
330676-02-3
Purity:
≥98%
Molecular Weight:
419.30
Molecular Formula:
C17H15BrN4O2S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
KH7 is a soluble A cyclase inhibitor.
KH7 (CAS 330676-02-3) References
- Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cells. | Hallows, KR., et al. 2009. J Biol Chem. 284: 5774-83. PMID: 19126549
- Lipoic acid stimulates cAMP production via G protein-coupled receptor-dependent and -independent mechanisms. | Salinthone, S., et al. 2011. J Nutr Biochem. 22: 681-90. PMID: 21036588
- Intramitochondrial adenylyl cyclase controls the turnover of nuclear-encoded subunits and activity of mammalian complex I of the respiratory chain. | De Rasmo, D., et al. 2015. Biochim Biophys Acta. 1853: 183-91. PMID: 25409931
- Lipopolysaccharide-induced pulmonary endothelial barrier disruption and lung edema: critical role for bicarbonate stimulation of AC10. | Nickols, J., et al. 2015. Am J Physiol Lung Cell Mol Physiol. 309: L1430-7. PMID: 26475732
- Acrosomal Swelling Is Triggered by cAMP Downstream of the Opening of Store-Operated Calcium Channels During Acrosomal Exocytosis in Human Sperm. | Sosa, CM., et al. 2016. Biol Reprod. 94: 57. PMID: 26792943
- Alcohol Decreases Organic Dust-Stimulated Airway Epithelial TNF-Alpha Through a Nitric Oxide and Protein Kinase-Mediated Inhibition of TACE. | Gerald, CL., et al. 2016. Alcohol Clin Exp Res. 40: 273-83. PMID: 26842246
- Soluble Adenylyl Cyclase Regulates Bile Salt-Induced Apoptosis in Human Cholangiocytes. | Chang, JC., et al. 2016. Hepatology. 64: 522-34. PMID: 26991014
- Bisphenol A accelerates capacitation-associated protein tyrosine phosphorylation of rat sperm by activating protein kinase A. | Wan, X., et al. 2016. Acta Biochim Biophys Sin (Shanghai). 48: 573-80. PMID: 27174873
- Soluble adenylyl cyclase is an acid-base sensor in epithelial base-secreting cells. | Roa, JN. and Tresguerres, M. 2016. Am J Physiol Cell Physiol. 311: C340-9. PMID: 27335168
- Ocean acidification stimulates alkali signal pathway: A bicarbonate sensing soluble adenylyl cyclase from oyster Crassostrea gigas mediates physiological changes induced by CO2 exposure. | Wang, X., et al. 2016. Aquat Toxicol. 181: 124-135. PMID: 27837685
- Abnormal Mitochondrial cAMP/PKA Signaling Is Involved in Sepsis-Induced Mitochondrial and Myocardial Dysfunction. | Neviere, R., et al. 2016. Int J Mol Sci. 17: PMID: 27973394
- Perfused Gills Reveal Fundamental Principles of pH Regulation and Ammonia Homeostasis in the Cephalopod Octopus vulgaris. | Hu, MY., et al. 2017. Front Physiol. 8: 162. PMID: 28373845
- Soluble adenylyl cyclase mediates mitochondrial pathway of apoptosis and ATP metabolism in oyster Crassostrea gigas exposed to elevated CO2. | Wang, X., et al. 2017. Fish Shellfish Immunol. 66: 140-147. PMID: 28476673
- Extracellular cAMP activates molecular signalling pathways associated with sperm capacitation in bovines. | Alonso, CAI., et al. 2017. Mol Hum Reprod. 23: 521-534. PMID: 28521061
- Salt-induced Na+/K+-ATPase-α/β expression involves soluble adenylyl cyclase in endothelial cells. | Mewes, M., et al. 2017. Pflugers Arch. 469: 1401-1412. PMID: 28550472
Inhibitor of:
A cyclase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KH7, 5 mg | sc-252933 | 5 mg | $193.00 | |||
KH7, 10 mg | sc-252933A | 10 mg | $258.00 | |||
KH7, 25 mg | sc-252933B | 25 mg | $453.00 | |||
KH7, 50 mg | sc-252933C | 50 mg | $813.00 |