Keratin 33B Antibody (S-28): sc-100928

Keratin 33B Antibody (S-28) is a mouse monoclonal IgG2b kappa light chain antibody that detects the Keratin 33B protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Keratin 33B antibody (S-28) is available as a non-conjugated format. Keratin 33B is a member of the keratin family, which plays a crucial role in the structural integrity and resilience of epithelial tissues. Keratin 33B (S-28) antibody targets a protein primarily located in the cytoplasm of epithelial cells, where Keratin 33B contributes to the formation of intermediate filaments, providing mechanical support and protection against stress. Keratin 33B expression is particularly important in the skin and hair follicles, as Keratin 33B helps maintain the structural framework necessary for proper tissue functioning. Keratin 33B is involved in the regulation of cell proliferation and differentiation, making Keratin 33B essential for wound healing and tissue regeneration. Keratin 33B gene is located on human chromosome 17q21.2, and Keratin 33B expression is tightly regulated during various stages of development and in response to environmental stimuli. With a significant role in maintaining cellular architecture and function, Keratin 33B serves as a valuable target for research in dermatological and hair-related studies.

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Keratin 33B Antibody (S-28) References:

1. The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.  |  Langbein, L., et al. 1999. J Biol Chem. 274: 19874-84. PMID: 10391933
2. The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.  |  Rogers, MA., et al. 2004. Differentiation. 72: 527-40. PMID: 15617563
3. New consensus nomenclature for mammalian keratins.  |  Schweizer, J., et al. 2006. J Cell Biol. 174: 169-74. PMID: 16831889
4. K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle.  |  Langbein, L., et al. 2006. J Invest Dermatol. 126: 2377-86. PMID: 16874310
5. The complement of native alpha-keratin polypeptides of hair-forming cells: a subset of eight polypeptides that differ from epithelial cytokeratins.  |  Heid, HW., et al. 1986. Differentiation. 32: 101-19. PMID: 2431943
6. Sequence data and chromosomal localization of human type I and type II hair keratin genes.  |  Rogers, MA., et al. 1995. Exp Cell Res. 220: 357-62. PMID: 7556444
7. Sequences and differential expression of three novel human type-II hair keratins.  |  Rogers, MA., et al. 1997. Differentiation. 61: 187-94. PMID: 9084137
8. Characterization and chromosomal localization of human hair-specific keratin genes and comparative expression during the hair growth cycle.  |  Bowden, PE., et al. 1998. J Invest Dermatol. 110: 158-64. PMID: 9457912

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Keratin 33B Antibody (S-28) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-Keratin 33B Antibody (S-28) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Keratin 33B Antibody (S-28) Specifications

Alternate Product Name: Keratin 33B

Product Clone Name: S-28

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 1-405

Epitope Target: Keratin 33B

Epitope Species: human

Product Reactivity/Detection: Keratin 33B

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 100 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Keratin 33B Antibody (S-28): N/A