KDdiA-PC (CAS 439904-34-4)

KDdiA-PC, with CAS number 439904-34-4, is a phosphatidylcholine derivative featuring two unusual fatty acyl chains, known to be ketodecanoic (KD) and diarachidonoyl (diA), attached to a glycerophosphocholine backbone. This distinctive structural composition makes KDdiA-PC a focal point in specialized biochemical and biophysical research, particularly in the study of lipid membranes′ properties and functions. The ketodecanoic acid component introduces ketone functionality, which impacts the intermolecular interactions within lipid bilayers and influences the overall membrane dynamics, fluidity, and phase behavior. The diarachidonoyl component, rich in arachidonic acid, a polyunsaturated fatty acid, contributes to studying lipid peroxidation processes and the role of highly unsaturated lipid environments in cellular signaling pathways. KDdiA-PC is extensively used in the creation of model membranes to simulate and understand the behavior of biologically relevant lipid mixtures, providing crucial insights into the physical properties of cell membranes under various physiological conditions. Researchers also utilize this compound to explore the impact of ketone groups within phospholipids on the stability and functionality of membranes, which is essential for understanding lipid-mediated cellular processes and the biophysics of membrane-associated proteins and enzymes. Through such studies, KDdiA-PC aids in advancing our comprehension of lipid biochemistry and its implications in cellular structure and function.