Molecular structure of Kasugamycin hydrochloride, CAS Number: 19408-46-9
Kasugamycin hydrochloride (CAS 19408-46-9)
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Alternate Names:
3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-D-arabino-hexopyranosyl]-D-chiro-inositol
Application:
Kasugamycin hydrochloride is an antibiotic aminoglycoside that inhibits protein synthesis
CAS Number:
19408-46-9
Purity:
≥90%
Molecular Weight:
415.82
Molecular Formula:
C14H25N3O9•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Streptomyces Kasugaensis, a type of actinomycete bacteria, produces an antibiotic known as Kasugamycin hydrochloride (KSH) that is utilized as a growth enhancer. KSH functions by obstructing the production of bacterial proteins via binding to a precise location on the 30S ribosomal subunit. This binding obstructs the formation of peptide bonds between amino acids during protein synthesis. The outcome of this inhibition of protein synthesis is bacterial death.
Kasugamycin hydrochloride (CAS 19408-46-9) References
- Localized mutagenesis of the aroE-strA section of the Escherichia coli chromosome coding for ribosomal proteins. | Berger, I., et al. 1975. Mol Gen Genet. 141: 207-11. PMID: 1107816
- Natural products that have been used commercially as crop protection agents. | Copping, LG. and Duke, SO. 2007. Pest Manag Sci. 63: 524-54. PMID: 17487882
- Exposure effect of fungicide kasugamycin on bacterial community in natural river sediment. | Huang, CY., et al. 2010. J Environ Sci Health B. 45: 485-91. PMID: 20512740
- The novel kasugamycin 2'-N-acetyltransferase gene aac(2')-IIa, carried by the IncP island, confers kasugamycin resistance to rice-pathogenic bacteria. | Yoshii, A., et al. 2012. Appl Environ Microbiol. 78: 5555-64. PMID: 22660700
- Repurposing of rutin for the inhibition of norovirus replication. | Chéron, N., et al. 2015. Arch Virol. 160: 2353-8. PMID: 26112762
- Multi-residue analysis of pesticides, plant hormones, veterinary drugs and mycotoxins using HILIC chromatography - MS/MS in various food matrices. | Danezis, GP., et al. 2016. Anal Chim Acta. 942: 121-138. PMID: 27720116
- Involvement of GcvB small RNA in intrinsic resistance to multiple aminoglycoside antibiotics in Escherichia coli. | Muto, A., et al. 2021. J Biochem. 169: 485-489. PMID: 33169170
- Mechanism of kasugamycin action on polypeptide synthesis. | Tanaka, N., et al. 1966. J Biochem. 60: 429-34. PMID: 5339117
- Chemical studies on kasugamycin. I. Acid degradation. | Suhara, Y., et al. 1965. J Antibiot (Tokyo). 18: 182-3. PMID: 5898333
- Sialyl Lewis X mimics derived from a pharmacophore search are selectin inhibitors with anti-inflammatory activity. | Rao, BN., et al. 1994. J Biol Chem. 269: 19663-6. PMID: 7519598
- Effects of antimutagens on development of drug/antibiotic resistance in microorganisms. | Pillai, SP. and Shankel, DM. 1998. Mutat Res. 402: 139-50. PMID: 9675262
- Effect of partial pesticide spraying on the number of major pests and damage to new shoots of tea plants | Satoshi Kakoki, Takeshi Kamimuro, Katsuo Tsuda, Yositaka Sakamaki. 2019. Journal of Asia-Pacific Entomology. Volume 22, Issue 3: 826-837.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Kasugamycin hydrochloride, 10 g | sc-252932 | 10 g | $316.00 |