karyopherin α1/6 Antibody (2D9): sc-101540
- karyopherin α1/6 Antibody (2D9) is a rat monoclonal IgG2a karyopherin α1/6 antibody, cited in 3 publications, provided at 200 µg/ml
- raised against full-length recombinant karyopherin α6 of mouse origin
- karyopherin alpha 1/6 Antibody (2D9) is recommended for detection of karyopherin α1 and karyopherin α6 of mouse, rat, human, hamster, bovine and monkey origin by WB, IP, IF and ELISA
- karyopherin alpha 1/6 Antibody (2D9) is available conjugated to agarose for IP; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for karyopherin α1/6 Antibody (2D9). This work is in progress.
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SEE ALSO...
Karyopherin α1/6 Antibody (2D9) is a rat monoclonal IgG2a antibody that detects karyopherin alpha 1/6 protein of mouse, rat, human, hamster, bovine, and monkey origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Karyopherin α1/6 (2D9) antibody is available in both non-conjugated and various conjugated forms, including agarose, phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Karyopherin alpha 1/6 protein plays a crucial role in nuclear import of proteins, specifically those containing nuclear localization signals (NLSs). These signals are essential for selective transport of proteins into the nucleus, where proteins can perform vital functions such as gene expression regulation and DNA repair. Karyopherin α1 and karyopherin α6 serve as adaptors for karyopherin β1, facilitating recognition and docking of NLS-containing proteins at the nuclear pore complex (NPC). Karyopherin α1 and karyopherin α6 include one importin β-binding (IBB) domain and ten armadillo (ARM) repeats, which are critical for binding and transporting substrates effectively. Through ensuring proper protein localization, karyopherin α1 and karyopherin α6 maintain cellular function and respond to various signaling pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
karyopherin α1/6 Antibody (2D9) | sc-101540 | 200 µg/ml | $322.00 | |||
karyopherin α1/6 Antibody (2D9) AC | sc-101540 AC | 500 µg/ml, 25% agarose | $424.00 | |||
karyopherin α1/6 Antibody (2D9) FITC | sc-101540 FITC | 200 µg/ml | $336.00 | |||
karyopherin α1/6 Antibody (2D9) PE | sc-101540 PE | 200 µg/ml | $349.00 | |||
karyopherin α1/6 Antibody (2D9) Alexa Fluor® 488 | sc-101540 AF488 | 200 µg/ml | $364.00 | |||
karyopherin α1/6 Antibody (2D9) Alexa Fluor® 546 | sc-101540 AF546 | 200 µg/ml | $364.00 | |||
karyopherin α1/6 Antibody (2D9) Alexa Fluor® 594 | sc-101540 AF594 | 200 µg/ml | $364.00 | |||
karyopherin α1/6 Antibody (2D9) Alexa Fluor® 647 | sc-101540 AF647 | 200 µg/ml | $364.00 | |||
karyopherin α1/6 Antibody (2D9) Alexa Fluor® 680 | sc-101540 AF680 | 200 µg/ml | $364.00 | |||
karyopherin α1/6 Antibody (2D9) Alexa Fluor® 790 | sc-101540 AF790 | 200 µg/ml | $364.00 |