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Kanamycin sulfate (CAS 70560-51-9)

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Application:
Kanamycin sulfate is an aminoglycoside-antibiotic with broad antibacterial spectrum
CAS Number:
70560-51-9
Molecular Weight:
582.58
Molecular Formula:
C18H36N4O11•H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Kanamycin sulfate is an aminoglycoside-antibiotic with broad antibacterial spectrum, including mycobacteria, many gram-positive and most gram-negative organisms. It binds to ribosomal components and inhibits protein synthesis. Kanamycin is inactivated by an aminoglycoside phospho transferase (MW 25,000) in the periplasmic space. It is a selectable marker for cosmid vectors used in transfection of mammalian cells.


Kanamycin sulfate (CAS 70560-51-9) References

  1. Development of liquid chromatographic method for the analysis of kanamycin residues in varicella vaccine using phenylisocyanate as a derivatization reagent.  |  Kim, BH., et al. 2001. J Chromatogr B Biomed Sci Appl. 752: 173-7. PMID: 11254192
  2. Development and validation of a simple capillary zone electrophoresis method for the analysis of kanamycin sulfate with UV detection after pre-capillary derivatization.  |  Kaale, E., et al. 2001. J Chromatogr A. 924: 451-8. PMID: 11521896
  3. Determination of kanamycin by electrophoretically mediated microanalysis with in-capillary derivatization and UV detection.  |  Kaale, E., et al. 2003. Electrophoresis. 24: 1119-25. PMID: 12658704
  4. The ototoxicity of Kanamycin sulfate in the presence of compromised renal function.  |  NAUNTON, RF. and WARD, PH. 1959. AMA Arch Otolaryngol. 69: 398-9. PMID: 13636577
  5. Crystal structure, conformation, and absolute configuration of kanamycin A.  |  Puius, YA., et al. 2006. Carbohydr Res. 341: 2871-5. PMID: 17052696
  6. [Ototoxicity of kanamycin sulfate in adult rats and its underlying mechanisms].  |  Zhang, ZC., et al. 2011. Sheng Li Xue Bao. 63: 171-6. PMID: 21505733
  7. [Research progress of acute kanamycin sulfate-induced deafness in guinea pig].  |  Yin, Z. and Kng, W. 2012. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 26: 478-80. PMID: 22870728
  8. Extraordinary sensitivity enhancement by metasurfaces in terahertz detection of antibiotics.  |  Xie, L., et al. 2015. Sci Rep. 5: 8671. PMID: 25728144
  9. The Effect of Kanamycin and Tetracycline on Growth and Photosynthetic Activity of Two Chlorophyte Algae.  |  Bashir, KM. and Cho, MG. 2016. Biomed Res Int. 2016: 5656304. PMID: 27747232
  10. Determination of kanamycin using a molecularly imprinted SPR sensor.  |  Zhang, L., et al. 2018. Food Chem. 266: 170-174. PMID: 30381173
  11. Efficacy of Switching from Kanamycin Sulfate to Rifaximin in Patients with Hepatic Cirrhosis.  |  Tatsumi, R., et al. 2021. Intern Med. 60: 1501-1507. PMID: 33361677
  12. Carbon dots derived from kanamycin sulfate with antibacterial activity and selectivity for Cr6+ detection.  |  Luo, Q., et al. 2021. Analyst. 146: 1965-1972. PMID: 33496685
  13. An edible kanamycin sulfate cross-linked cellulose active against multiple pathogenic bacteria.  |  Gu, J., et al. 2022. Int J Biol Macromol. 194: 435-444. PMID: 34801585
  14. PCN-222@g-C3N4 cathodic materials for 'signal-off' photoelectrochemical sensing of kanamycin sulfate.  |  Dong, W., et al. 2021. RSC Adv. 11: 28320-28325. PMID: 35480742
  15. Kanamycin sulfate in the horse: serum, synovial fluid, peritoneal fluid, and urine concentrations after single-dose intramuscular administration.  |  Brown, MP., et al. 1981. Am J Vet Res. 42: 1823-5. PMID: 7325450

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Kanamycin sulfate, 5 g

sc-257635
5 g
$85.00

Kanamycin sulfate, 25 g

sc-257635A
25 g
$126.00