Molecular structure of Kanamycin B sulfate, CAS Number: 29701-07-3
Kanamycin B sulfate (CAS 29701-07-3)
Alternate Names:
Bekanamycinsulfate salt
Application:
Kanamycin B sulfate is highly potent antibiotic against Gram-negative bacteria often used in cell culture
CAS Number:
29701-07-3
Purity:
≥95%
Molecular Weight:
581.59
Molecular Formula:
C18H37N5O10•H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Kanamycin B is an aminoglycoside with antibiotic properties that associates with bacterial ribosomal RNA. The compound is highly potent against gram-negative bacteria. Other members of the aminoglycoside group include Kanamycin A (sc-205358) and Amikacin (sc-202457). Kanamycin B has five amino groups and has a stronger association with acidic phospholipids in comparison to Kanamycin A. Studies have shown that the Kcat value of the kanamycin group is higher compared to the neomycin group.
Kanamycin B sulfate (CAS 29701-07-3) References
- In vitro selection of RNA against kanamycin B. | Kwon, M., et al. 2001. Mol Cells. 11: 303-11. PMID: 11459219
- The nebramycin aminoglycoside profiles of Streptomyces tenebrarius and their characterization using an integrated liquid chromatography-electrospray ionization-tandem mass spectrometric analysis. | Park, JW., et al. 2010. Anal Chim Acta. 661: 76-84. PMID: 20113718
- Thermodynamics and kinetics of association of antibiotics with the aminoglycoside acetyltransferase (3)-IIIb, a resistance-causing enzyme. | Norris, AL., et al. 2010. Biochemistry. 49: 4027-35. PMID: 20387903
- Kanamycin sensitivity of cultured tissues of Vitis. | Colby, SM. and Meredith, CP. 1990. Plant Cell Rep. 9: 237-40. PMID: 24226816
- Individual pK a Values of Tobramycin, Kanamycin B, Amikacin, Sisomicin, and Netilmicin Determined by Multinuclear NMR Spectroscopy. | Alkhzem, AH., et al. 2020. ACS Omega. 5: 21094-21103. PMID: 32875246
- Interaction of kanamycin A and kanamycin B with phospholipids. | Yung, MW. and Green, C. 1987. J Antibiot (Tokyo). 40: 862-7. PMID: 3610836
- Utilization of carbon and nitrogen sources by Streptomyces kanamyceticus for kanamycin production. | Basak, K. and Majumdar, SK. 1973. Antimicrob Agents Chemother. 4: 6-10. PMID: 4791483
- Resistance to antibiotic synergism in Streptococcus faecalis: further studies with amikacin and with a new amikacin derivative, 4'-deoxy, 6'-N-methylamikacin. | Calderwood, SB., et al. 1981. Antimicrob Agents Chemother. 19: 549-55. PMID: 6264851
- Comparison of the effects of amikacin and kanamycins A and B on dimyristoylphosphatidylglycerol bilayers. An infrared spectroscopic investigation. | Carrier, D., et al. 1997. Biochem Pharmacol. 53: 401-8. PMID: 9065744
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Kanamycin B sulfate, 250 mg | sc-202680 | 250 mg | $148.00 |