Date published: 2025-11-8

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Kanamycin A Monosulfate (CAS 25389-94-0)

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Alternate Names:
Kanamicina; Kanamycin
CAS Number:
25389-94-0
Purity:
≥98%
Molecular Weight:
582.58
Molecular Formula:
C18H36N4O11•H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Kanamycin A Monosulfate is an antibiotic that belongs to the family of aminoglycosides. The antibiotic associates with ribosomal RNA by forming a complex at the bacterial ribosomal A site. Studies show that when Kanamycin A and Neomycin B (sc-338359) are conjugated through lipid conjugation there is an increase of antibacterial activity against methicillin-resistant Staphylococcus epidermidis (MRSE) from Kanamycin A and methicillin-resistant Staphylococcus aureus (MRSA) from both antibiotics.


Kanamycin A Monosulfate (CAS 25389-94-0) References

  1. In vitro selection of RNA against kanamycin B.  |  Kwon, M., et al. 2001. Mol Cells. 11: 303-11. PMID: 11459219
  2. Preparation and screening of high-density cDNA arrays with genomic clones.  |  Zehetner, G., et al. 2001. Methods Mol Biol. 175: 169-88. PMID: 11462834
  3. Mycobacterium smegmatis D-Alanine Racemase Mutants Are Not Dependent on D-Alanine for Growth.  |  Chacon, O., et al. 2002. Antimicrob Agents Chemother. 46: 47-54. PMID: 11751110
  4. Effect of antibiotics on growth and laccase production from Cyathus bulleri and Pycnoporus cinnabarinus.  |  Dhawan, S., et al. 2005. Bioresour Technol. 96: 1415-8. PMID: 15792590
  5. Effect of Cu(II) on the complex between kanamycin A and the bacterial ribosomal A site.  |  Balenci, D., et al. 2008. Chembiochem. 9: 114-23. PMID: 18058790
  6. Antibacterial activity of guanidinylated neomycin B- and kanamycin A-derived amphiphilic lipid conjugates.  |  Bera, S., et al. 2010. J Antimicrob Chemother. 65: 1224-7. PMID: 20332193
  7. Colorimetric detection of kanamycin based on analyte-protected silver nanoparticles and aptamer-selective sensing mechanism.  |  Xu, Y., et al. 2015. Anal Chim Acta. 891: 298-303. PMID: 26388390
  8. SOD1 Lysine 123 Acetylation in the Adult Central Nervous System.  |  Kaliszewski, M., et al. 2016. Front Cell Neurosci. 10: 287. PMID: 28066183
  9. Assessing the Molecular Targets and Mode of Action of Furanone C-30 on Pseudomonas aeruginosa Quorum Sensing.  |  Markus, V., et al. 2021. Molecules. 26: PMID: 33803983
  10. Boron clusters as broadband membrane carriers.  |  Barba-Bon, A., et al. 2022. Nature. 603: 637-642. PMID: 35322251
  11. NADH dehydrogenase defects confer isoniazid resistance and conditional lethality in Mycobacterium smegmatis.  |  Miesel, L., et al. 1998. J Bacteriol. 180: 2459-67. PMID: 9573199
  12. Regioselective modification of amino groups in aminoglycosides based on cyclic carbamate formation  |  G Chen, P Pan, Y Yao, Y Chen, X Meng, Z Li. 2008. Tetrahedron. 64: 9078-9087.
  13. Synthesis and characterization of oligo aminoglycosides and polyethylenimine conjugates as polymeric gene carriers  |  , et al. 2023. Korean Journal of Chemical Engineering. 40: pages 325–336.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Kanamycin A Monosulfate, 1 g

sc-205358
1 g
$65.00

Kanamycin A Monosulfate, 5 g

sc-205358A
5 g
$164.00